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Nucleic Acids Research|April 7, 2022
Multivalent DNA and nucleosome acidic patch interactions specify VRK1 mitotic localization and activityGabrielle R Budziszewski, Yani Zhao, Cathy J Spangler, et al.Chemmedchem|December 30, 2016
Discovery of Macrocyclic Pyrimidines as MerTK-Specific InhibitorsAndrew L McIver, Weihe Zhang, Qingyang Liu, et al.ACS Chemical Biology|March 6, 2023
PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) ComponentsFrances M Bashore, Caroline A Foley, Han Wee Ong, et al.Journal of Medicinal Chemistry|April 11, 2025
Discovery of Novel TYRO3/MERTK Dual InhibitorsDeyu Kong, Jichen Zhao, Daowei Huang, et al.Journal of Medicinal Chemistry|October 23, 2018
Highly Selective MERTK Inhibitors Achieved by a Single Methyl GroupJichen Zhao, Dehui Zhang, Weihe Zhang, et al.European Journal of Medicinal Chemistry|April 4, 2025
Exploiting structural variability in the kinase back-pocket to modulate polypharmacology of TAM inhibitorsMegan D Hopkins, Dehui Zhang, Zhilong Chen, et al.Journal of Medicinal Chemistry|July 29, 2014
UNC2025, a potent and orally bioavailable MER/FLT3 dual inhibitorWeihe Zhang, Deborah DeRyckere, Debra Hunter, et al.European Journal of Medicinal Chemistry|May 23, 2013
UNC1062, a new and potent Mer inhibitorJing Liu, Weihe Zhang, Michael A Stashko, et al.JCI Insight|May 10, 2016
The MERTK/FLT3 inhibitor MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemiaKatherine A Minson, Catherine C Smith, Deborah DeRyckere, et al.European Journal of Medicinal Chemistry|March 8, 2026
Identification and optimization of first-in-class RNA helicase inhibitors of DDX1, LGP2, and MDA5Xiaowen Wang, Feijun Wang, Deyu Kong, et al.Pageof 6