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Bioorganic & Medicinal Chemistry Letters|July 21, 2022
Bicyclic pyrimidine compounds as potent IRAK4 inhibitorsYan Chen, Kin Tso, Thilo J Heckrodt, et al.
The Journal of Allergy and Clinical Immunology|September 5, 2006
Identification of the Syk kinase inhibitor R112 by a human mast cell screenAlexander B Rossi, Ellen Herlaar, Sylvia Braselmann, et al.
Bioorganic & Medicinal Chemistry Letters|October 15, 2015
Developing structure-activity relationships from an HTS hit for inhibition of the Cks1-Skp2 protein-protein interactionRajinder Singh, Arvinder Sran, David C Carroll, et al.
Journal of Immunology (Baltimore, Md. : 1950)|July 15, 2009
JAK3 inhibition significantly attenuates psoriasiform skin inflammation in CD18 mutant PL/J miceBetty Y Chang, Feifei Zhao, Xiaodong He, et al.
Arthritis and Rheumatism|April 29, 2008
An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupusFrances Rena Bahjat, Polly R Pine, Andrea Reitsma, et al.
BMC Research Notes|September 26, 2014
Global metabolite profiling of mice with high-fat diet-induced obesity chronically treated with AMPK activators R118 or metformin reveals tissue-selective alterations in metabolic pathwaysYonchu Jenkins, Tian-Qiang Sun, Yingwu Li, et al.
Plos One|April 9, 2014
Noninvasive imaging of in vivo MuRF1 expression during muscle atrophyWei Li, Mark D Claypool, Annabelle M Friera, et al.
Bioorganic & Medicinal Chemistry Letters|April 16, 2015
Application of cultured human mast cells (CHMC) for the design and structure-activity relationship of IgE-mediated mast cell activation inhibitorsAnkush Argade, Somasekhar Bhamidipati, Hui Li, et al.
Chemistry & Biology|October 27, 2007
A class of small molecules that inhibit TNFalpha-induced survival and death pathways via prevention of interactions between TNFalphaRI, TRADD, and RIP1Tarikere L Gururaja, Stephanie Yung, Rongxian Ding, et al.
Bioorganic & Medicinal Chemistry|August 16, 2022
Structure activity relationships leading to the identification of the indirect activator of AMPK, R419Simon J Shaw, Dane A Goff, David C Carroll, et al.
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