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Clinical Pharmacokinetics
|
December 17, 2003
Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes
Hongbing Wang, Edward L LeCluyse
Methods in Molecular Biology (Clifton, N.J.)
|
July 21, 2010
Isolation and culture of primary hepatocytes from resected human liver tissue
Edward L Lecluyse, Eliane Alexandre
Assay and Drug Development Technologies
|
January 22, 2014
A micropatterned hepatocyte coculture model for assessment of liver toxicity using high-content imaging analysis
O Joseph Trask, Amanda Moore, Edward L LeCluyse
ILAR Journal
|
January 6, 2017
The Promise of New Technologies to Reduce, Refine, or Replace Animal Use while Reducing Risks of Drug Induced Liver Injury in Pharmaceutical Development
Frank D Sistare, William B Mattes, Edward L LeCluyse
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
March 25, 2025
Quantitative clinical risk assessment of CYP2C, UDP-glucuronosyltransferase, P-glycoprotein induction, and complex drug-drug interactions using TruVivo human hepatocyte triculture platform
Diane Ramsden, Cody L Fullenwider, Cipriano Santos, et al.
Molecular Pharmacology
|
August 16, 2002
Regulation of human CYP2C9 by the constitutive androstane receptor: discovery of a new distal binding site
Stephen S Ferguson, Edward L LeCluyse, Masahiko Negishi, et al.
Journal of Biochemical and Molecular Toxicology
|
April 26, 2005
Modulation of UDP-glucuronosyltransferase 1A1 in primary human hepatocytes by prototypical inducers
Cornelia M Smith, Stephanie R Faucette, Hongbing Wang, et al.
Toxicology Research
|
March 16, 2013
<i>In vitro</i> models for liver toxicity testing
Valerie Y Soldatow, Edward L Lecluyse, Linda G Griffith, et al.
Journal of Biochemical and Molecular Toxicology
|
February 10, 2009
Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes
Jasminder Sahi, Stacy S Shord, Celeste Lindley, et al.
Molecular Pharmacology
|
September 24, 2004
The human sulfotransferase SULT1A1 gene is regulated in a synergistic manner by Sp1 and GA binding protein
Nadine Hempel, Hongbing Wang, Edward L LeCluyse, et al.
Page
of 7
Search research articles
Search
Showing results (1-10 of 66) with videos related to
Sort By:
Page
of 7
Clinical Pharmacokinetics
|
December 17, 2003
Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes
Hongbing Wang, Edward L LeCluyse
Methods in Molecular Biology (Clifton, N.J.)
|
July 21, 2010
Isolation and culture of primary hepatocytes from resected human liver tissue
Edward L Lecluyse, Eliane Alexandre
Assay and Drug Development Technologies
|
January 22, 2014
A micropatterned hepatocyte coculture model for assessment of liver toxicity using high-content imaging analysis
O Joseph Trask, Amanda Moore, Edward L LeCluyse
ILAR Journal
|
January 6, 2017
The Promise of New Technologies to Reduce, Refine, or Replace Animal Use while Reducing Risks of Drug Induced Liver Injury in Pharmaceutical Development
Frank D Sistare, William B Mattes, Edward L LeCluyse
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
March 25, 2025
Quantitative clinical risk assessment of CYP2C, UDP-glucuronosyltransferase, P-glycoprotein induction, and complex drug-drug interactions using TruVivo human hepatocyte triculture platform
Diane Ramsden, Cody L Fullenwider, Cipriano Santos, et al.
Molecular Pharmacology
|
August 16, 2002
Regulation of human CYP2C9 by the constitutive androstane receptor: discovery of a new distal binding site
Stephen S Ferguson, Edward L LeCluyse, Masahiko Negishi, et al.
Journal of Biochemical and Molecular Toxicology
|
April 26, 2005
Modulation of UDP-glucuronosyltransferase 1A1 in primary human hepatocytes by prototypical inducers
Cornelia M Smith, Stephanie R Faucette, Hongbing Wang, et al.
Toxicology Research
|
March 16, 2013
<i>In vitro</i> models for liver toxicity testing
Valerie Y Soldatow, Edward L Lecluyse, Linda G Griffith, et al.
Journal of Biochemical and Molecular Toxicology
|
February 10, 2009
Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes
Jasminder Sahi, Stacy S Shord, Celeste Lindley, et al.
Molecular Pharmacology
|
September 24, 2004
The human sulfotransferase SULT1A1 gene is regulated in a synergistic manner by Sp1 and GA binding protein
Nadine Hempel, Hongbing Wang, Edward L LeCluyse, et al.
Page
of 7