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International Journal of Molecular Sciences|December 9, 2023
A New Drug Discovery Platform: Application to DNA Polymerase Eta and Apurinic/Apyrimidinic Endonuclease 1Debanu Das, Matthew A J Duncton, Taxiarchis M Georgiadis, et al.
ACS Sensors|November 22, 2023
Imaging the Bacterial Cell Wall Using N-Acetyl Muramic Acid-Derived Positron Emission Tomography RadiotracersSang Hee Lee, Jung Min Kim, Marina López-Álvarez, et al.
Oncotarget|May 17, 2014
Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapyRachel Abbotts, Rosalyn Jewell, Jérémie Nsengimana, et al.
Bioorganic & Medicinal Chemistry Letters|November 2, 2005
The identification of potent and selective imidazole-based inhibitors of B-Raf kinaseAndrew K Takle, Murray J B Brown, Susannah Davies, et al.
Psychopharmacology|September 3, 2008
Preclinical investigations into the antipsychotic potential of the novel histamine H3 receptor antagonist GSK207040Eric Southam, Jackie Cilia, Jane E Gartlon, et al.
Communications Biology|May 13, 2024
Metabolism-driven in vitro/in vivo disconnect of an oral ERɑ VHL-PROTACThomas G Hayhow, Beth Williamson, Mandy Lawson, et al.
ACS Central Science|March 4, 2020
Sensing Living Bacteria in Vivo Using d-Alanine-Derived 11C RadiotracersMatthew F L Parker, Justin M Luu, Brailee Schulte, et al.
Biomedical Microdevices|October 26, 2016
In vitro clearance of doxorubicin with a DNA-based filtration device designed for intravascular use with intra-arterial chemotherapyMariam S Aboian, Jay F Yu, Ayushi Gautam, et al.
STAR Protocols|June 29, 2024
Protocol for producing hyperpolarized 13C-bicarbonate for clinical MRI of extracellular pH in aggressive tumorsChanghua Mu, Xiaoxi Liu, Andrew Riselli, et al.
Journal of Medicinal Chemistry|September 12, 2018
Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal TumorsJason G Kettle, Rana Anjum, Evan Barry, et al.
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