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Nature Reviews. Drug Discovery
|
July 8, 2017
Opportunities and challenges in phenotypic drug discovery: an industry perspective
John G Moffat, Fabien Vincent, Jonathan A Lee, et al.
Nature Reviews. Drug Discovery
|
May 31, 2022
Phenotypic drug discovery: recent successes, lessons learned and new directions
Fabien Vincent, Arsenio Nueda, Jonathan Lee, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 24, 2009
Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors
Fabien Vincent, Margaret T Nguyen, Daniel E Emerling, et al.
Molecular Biology of the Cell
|
May 16, 2008
Novel genetic tools reveal Cdk5's major role in Golgi fragmentation in Alzheimer's disease
Kai-Hui Sun, Yolanda de Pablo, Fabien Vincent, et al.
Lupus Science & Medicine
|
February 24, 2022
Type 1 interferon status in systemic lupus erythematosus: a longitudinal analysis
Melissa Northcott, Sarah Jones, Rachel Koelmeyer, et al.
ACS Chemical Biology
|
May 13, 2014
ATP-mediated kinome selectivity: the missing link in understanding the contribution of individual JAK Kinase isoforms to cellular signaling
Atli Thorarensen, Mary Ellen Banker, Andrew Fensome, et al.
Cell Chemical Biology
|
September 5, 2020
Hit Triage and Validation in Phenotypic Screening: Considerations and Strategies
Fabien Vincent, Paula M Loria, Andrea D Weston, et al.
Bioorganic & Medicinal Chemistry
|
December 7, 2020
The advantages of describing covalent inhibitor in vitro potencies by IC<sub>50</sub> at a fixed time point. IC<sub>50</sub> determination of covalent inhibitors provides meaningful data to medicinal chemistry for SAR optimization
Atli Thorarensen, Paul Balbo, Mary E Banker, et al.
Science Translational Medicine
|
June 26, 2015
Developing predictive assays: the phenotypic screening "rule of 3"
Fabien Vincent, Paula Loria, Marko Pregel, et al.
Plos One
|
March 27, 2018
Class I HDAC inhibition is a novel pathway for regulating astrocytic apoE secretion
Erica Dresselhaus, James M Duerr, Fabien Vincent, et al.
Page
of 5
Search research articles
Search
Showing results (11-20 of 42) with videos related to
Sort By:
Page
of 5
Nature Reviews. Drug Discovery
|
July 8, 2017
Opportunities and challenges in phenotypic drug discovery: an industry perspective
John G Moffat, Fabien Vincent, Jonathan A Lee, et al.
Nature Reviews. Drug Discovery
|
May 31, 2022
Phenotypic drug discovery: recent successes, lessons learned and new directions
Fabien Vincent, Arsenio Nueda, Jonathan Lee, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 24, 2009
Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors
Fabien Vincent, Margaret T Nguyen, Daniel E Emerling, et al.
Molecular Biology of the Cell
|
May 16, 2008
Novel genetic tools reveal Cdk5's major role in Golgi fragmentation in Alzheimer's disease
Kai-Hui Sun, Yolanda de Pablo, Fabien Vincent, et al.
Lupus Science & Medicine
|
February 24, 2022
Type 1 interferon status in systemic lupus erythematosus: a longitudinal analysis
Melissa Northcott, Sarah Jones, Rachel Koelmeyer, et al.
ACS Chemical Biology
|
May 13, 2014
ATP-mediated kinome selectivity: the missing link in understanding the contribution of individual JAK Kinase isoforms to cellular signaling
Atli Thorarensen, Mary Ellen Banker, Andrew Fensome, et al.
Cell Chemical Biology
|
September 5, 2020
Hit Triage and Validation in Phenotypic Screening: Considerations and Strategies
Fabien Vincent, Paula M Loria, Andrea D Weston, et al.
Bioorganic & Medicinal Chemistry
|
December 7, 2020
The advantages of describing covalent inhibitor in vitro potencies by IC<sub>50</sub> at a fixed time point. IC<sub>50</sub> determination of covalent inhibitors provides meaningful data to medicinal chemistry for SAR optimization
Atli Thorarensen, Paul Balbo, Mary E Banker, et al.
Science Translational Medicine
|
June 26, 2015
Developing predictive assays: the phenotypic screening "rule of 3"
Fabien Vincent, Paula Loria, Marko Pregel, et al.
Plos One
|
March 27, 2018
Class I HDAC inhibition is a novel pathway for regulating astrocytic apoE secretion
Erica Dresselhaus, James M Duerr, Fabien Vincent, et al.
Page
of 5