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Biorxiv : the Preprint Server for Biology|September 5, 2025
As48, a First-in-Class Dual-Function TREM2 Modulator: Receptor Activation and Shedding InhibitionSungwoo Cho, Farida El Gaamouch, Saurabh Upadhyay, et al.
ACS Medicinal Chemistry Letters|August 20, 2025
Discovery of a Small Molecule TREM2 Agonist with Improved In Vitro Pharmacokinetic Profile and Validated Target EngagementShaoren Yuan, Farida El Gaamouch, Sungwoo Cho, et al.
Proceedings of the National Academy of Sciences of the United States of America|July 28, 2010
CaMKII control of spine size and synaptic strength: role of phosphorylation states and nonenzymatic actionHyun Jae Pi, Nikolai Otmakhov, Farida El Gaamouch, et al.
ACS Medicinal Chemistry Letters|February 18, 2026
AI-Assisted Discovery and Optimization of Small-Molecule TREM2 Agonists with Functional Microglial ActivitySungwoo Cho, Tibor Viktor Szalai, Farida El Gaamouch, et al.
Biorxiv : the Preprint Server for Biology|September 26, 2025
AI-Assisted Discovery and Optimization of Small Molecule TREM2 Agonists with Functional Microglial ActivitySungwoo Cho, Tibor Viktor Szalai, Farida El Gaamouch, et al.
Frontiers in Aging Neuroscience|December 30, 2022
Benefits of dietary polyphenols in Alzheimer's diseaseFarida El Gaamouch, Fiona Chen, Lap Ho, et al.
European Journal of Medicinal Chemistry|November 15, 2025
TREM2 activation by first-in-class direct small molecule agonists: DEL screening, optimization, biophysical validation, and functional characterizationHossam Nada, Shaoren Yuan, Farida El Gaamouch, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|August 3, 2012
Interaction between αCaMKII and GluN2B controls ERK-dependent plasticityFarida El Gaamouch, Alain Buisson, Olivier Moustié, et al.
Biorxiv : the Preprint Server for Biology|September 5, 2025
Structure-Based Virtual Screening Identifies TREM2-Targeted Small Molecules that Enhance Microglial PhagocytosisSungwoo Cho, Baljit Kaur, Kevin Lam, et al.
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