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Science Advances|April 15, 2020
Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiationRoberto Ravasio, Elena Ceccacci, Luciano Nicosia, et al.Journal of Medicinal Chemistry|December 26, 2015
Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor AgentPaola Vianello, Oronza A Botrugno, Anna Cappa, et al.Journal of Medicinal Chemistry|March 5, 2025
Design of Benzyl-triazolopyrimidine-Based NADPH Oxidase Inhibitors Leads to the Discovery of a Potent Dual Covalent NOX2/MAOB InhibitorBeatrice Noce, Sara Marchese, Marta Massari, et al.ACS Chemical Biology|June 1, 2013
Protein recognition by short peptide reversible inhibitors of the chromatin-modifying LSD1/CoREST lysine demethylaseMarcello Tortorici, Maria Teresa Borrello, Maria Tardugno, et al.Nature Immunology|September 22, 2022
Memory CD8<sup>+</sup> T cell diversity and B cell responses correlate with protection against SARS-CoV-2 following mRNA vaccinationNadia Brasu, Ines Elia, Valentina Russo, et al.Iscience|July 20, 2022
Fine-tuned KDM1A alternative splicing regulates human cardiomyogenesis through an enzymatic-independent mechanismVeronica Astro, Gustavo Ramirez-Calderon, Roberta Pennucci, et al.European Journal of Medicinal Chemistry|March 14, 2015
Pure enantiomers of benzoylamino-tranylcypromine: LSD1 inhibition, gene modulation in human leukemia cells and effects on clonogenic potential of murine promyelocytic blastsSergio Valente, Veronica Rodriguez, Ciro Mercurio, et al.Journal of Medical Genetics|May 27, 2019
Pathogenic variants in <i>PLOD3</i> result in a Stickler syndrome-like connective tissue disorder with vascular complicationsLisa Jean Ewans, Alison Colley, Carles Gaston-Massuet, et al.Nature Communications|August 12, 2021
A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosisDavide Pradella, Gianluca Deflorian, Alex Pezzotta, et al.ACS Infectious Diseases|May 6, 2017
A Phenotypic Based Target Screening Approach Delivers New Antitubercular CTP Synthetase InhibitorsMarta Esposito, Sára Szadocka, Giulia Degiacomi, et al.Pageof 26