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European Journal of Medicinal Chemistry
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March 16, 2018
Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibitor for PDGFRα driving chronic eosinophilic leukemia
Qiang Wang, Feiyang Liu, Shuang Qi, et al.
Cancer Letters
|
January 27, 2019
Repurposing cabozantinib to GISTs: Overcoming multiple imatinib-resistant cKIT mutations including gatekeeper and activation loop mutants in GISTs preclinical models
Tingting Lu, Cheng Chen, Aoli Wang, et al.
ACS Chemical Biology
|
April 19, 2013
Discovery of a selective irreversible BMX inhibitor for prostate cancer
Feiyang Liu, Xin Zhang, Ellen Weisberg, et al.
European Journal of Medicinal Chemistry
|
September 26, 2018
Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino)cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor
Beilei Wang, Jiaxin Wu, Yun Wu, et al.
Therapeutic Advances in Medical Oncology
|
June 18, 2019
Axitinib overcomes multiple imatinib resistant cKIT mutations including the gatekeeper mutation T670I in gastrointestinal stromal tumors
Feiyang Liu, Fengming Zou, Cheng Chen, et al.
Journal of Medicinal Chemistry
|
August 23, 2016
Discovery of N-((1-(4-(3-(3-((6,7-Dimethoxyquinolin-3-yl)oxy)phenyl)ureido)-2-(trifluoromethyl)phenyl)piperidin-4-yl)methyl)propionamide (CHMFL-KIT-8140) as a Highly Potent Type II Inhibitor Capable of Inhibiting the T670I "Gatekeeper" Mutant of cKIT Kinase
Binhua Li, Aoli Wang, Juan Liu, et al.
Oncotarget
|
April 14, 2016
Dual inhibition of AKT/FLT3-ITD by A674563 overcomes FLT3 ligand-induced drug resistance in FLT3-ITD positive AML
Aoli Wang, Hong Wu, Cheng Chen, et al.
Oncotarget
|
June 21, 2016
Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML)
Feiyang Liu, Beilei Wang, Qiang Wang, et al.
Oncotarget
|
April 16, 2016
Characterization of selective and potent PI3Kδ inhibitor (PI3KDIN- 015) for B-Cell malignances
Xiaochuan Liu, Aoli Wang, Xiaofei Liang, et al.
Oncotarget
|
July 23, 2016
Simultaneous inhibition of Vps34 kinase would enhance PI3Kδ inhibitor cytotoxicity in the B-cell malignancies
Xiaochuan Liu, Aoli Wang, Xiaofei Liang, et al.
Page
of 9
Search research articles
Search
Showing results (71-80 of 83) with videos related to
Sort By:
Page
of 9
European Journal of Medicinal Chemistry
|
March 16, 2018
Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibitor for PDGFRα driving chronic eosinophilic leukemia
Qiang Wang, Feiyang Liu, Shuang Qi, et al.
Cancer Letters
|
January 27, 2019
Repurposing cabozantinib to GISTs: Overcoming multiple imatinib-resistant cKIT mutations including gatekeeper and activation loop mutants in GISTs preclinical models
Tingting Lu, Cheng Chen, Aoli Wang, et al.
ACS Chemical Biology
|
April 19, 2013
Discovery of a selective irreversible BMX inhibitor for prostate cancer
Feiyang Liu, Xin Zhang, Ellen Weisberg, et al.
European Journal of Medicinal Chemistry
|
September 26, 2018
Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino)cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor
Beilei Wang, Jiaxin Wu, Yun Wu, et al.
Therapeutic Advances in Medical Oncology
|
June 18, 2019
Axitinib overcomes multiple imatinib resistant cKIT mutations including the gatekeeper mutation T670I in gastrointestinal stromal tumors
Feiyang Liu, Fengming Zou, Cheng Chen, et al.
Journal of Medicinal Chemistry
|
August 23, 2016
Discovery of N-((1-(4-(3-(3-((6,7-Dimethoxyquinolin-3-yl)oxy)phenyl)ureido)-2-(trifluoromethyl)phenyl)piperidin-4-yl)methyl)propionamide (CHMFL-KIT-8140) as a Highly Potent Type II Inhibitor Capable of Inhibiting the T670I "Gatekeeper" Mutant of cKIT Kinase
Binhua Li, Aoli Wang, Juan Liu, et al.
Oncotarget
|
April 14, 2016
Dual inhibition of AKT/FLT3-ITD by A674563 overcomes FLT3 ligand-induced drug resistance in FLT3-ITD positive AML
Aoli Wang, Hong Wu, Cheng Chen, et al.
Oncotarget
|
June 21, 2016
Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML)
Feiyang Liu, Beilei Wang, Qiang Wang, et al.
Oncotarget
|
April 16, 2016
Characterization of selective and potent PI3Kδ inhibitor (PI3KDIN- 015) for B-Cell malignances
Xiaochuan Liu, Aoli Wang, Xiaofei Liang, et al.
Oncotarget
|
July 23, 2016
Simultaneous inhibition of Vps34 kinase would enhance PI3Kδ inhibitor cytotoxicity in the B-cell malignancies
Xiaochuan Liu, Aoli Wang, Xiaofei Liang, et al.
Page
of 9