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Clinical Pharmacology in Drug Development
|
October 22, 2025
Assessment of Pharmacokinetic Drug Interaction of Asciminib with Atorvastatin in Healthy Participants
Matthias Hoch, Wendy Weis, Felix Huth, et al.
Pharmaceuticals (Basel, Switzerland)
|
March 28, 2026
Physiologically-Based Pharmacokinetics of Ribociclib Drug-Drug Interactions and Organ Impairment Pharmacokinetics in Early Breast Cancer
Yan Ji, Felix Huth, Craig Wang, et al.
Clinical Pharmacology and Therapeutics
|
June 20, 2020
Ribociclib Drug-Drug Interactions: Clinical Evaluations and Physiologically-Based Pharmacokinetic Modeling to Guide Drug Labeling
Tanay S Samant, Felix Huth, Kenichi Umehara, et al.
Clinical Pharmacology and Therapeutics
|
November 15, 2017
Ribociclib Bioavailability Is Not Affected by Gastric pH Changes or Food Intake: In Silico and Clinical Evaluations
Tanay S Samant, Shyeilla Dhuria, Yasong Lu, et al.
Clinical Pharmacokinetics
|
March 18, 2026
Pharmacokinetics of Asciminib 200 mg in the Presence of a Strong CYP3A4 Inducer, Phenytoin, in Healthy Participants
Matthias Hoch, Amanda J Taylor, Felix Huth, et al.
Molecular Pharmaceutics
|
June 7, 2023
Interlaboratory Variability in the Madin-Darby Canine Kidney Cell Proteome
Matthew D Harwood, Katharina Zettl, Manuel Weinheimer, et al.
Archives of Toxicology
|
July 18, 2024
Identification of reversible OATP1B1 and time-dependent CYP3A4 inhibition as the major risk factors for drug-induced cholestasis (DIC)
Vlasia Kastrinou-Lampou, Raquel Rodríguez-Pérez, Birk Poller, et al.
Clinical Pharmacokinetics
|
October 29, 2024
Clinical Pharmacology of Asciminib: A Review
Matthias Hoch, Felix Huth, Paul William Manley, et al.
Clinical Pharmacology and Therapeutics
|
September 26, 2023
Utilization of OATP1B Biomarker Coproporphyrin-I to Guide Drug-Drug Interaction Risk Assessment: Evaluation by the Pharmaceutical Industry
Ryota Kikuchi, Paresh P Chothe, Xiaoyan Chu, et al.
Drug Metabolism and Pharmacokinetics
|
January 6, 2026
Future directions in drug-drug interaction evaluations: Industry perspective on the ICH M12 guidance
Kenichi Umehara, Andrew Harrell, Chandra Prakash, et al.
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Search research articles
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Showing results (31-40 of 46) with videos related to
Sort By:
Page
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Clinical Pharmacology in Drug Development
|
October 22, 2025
Assessment of Pharmacokinetic Drug Interaction of Asciminib with Atorvastatin in Healthy Participants
Matthias Hoch, Wendy Weis, Felix Huth, et al.
Pharmaceuticals (Basel, Switzerland)
|
March 28, 2026
Physiologically-Based Pharmacokinetics of Ribociclib Drug-Drug Interactions and Organ Impairment Pharmacokinetics in Early Breast Cancer
Yan Ji, Felix Huth, Craig Wang, et al.
Clinical Pharmacology and Therapeutics
|
June 20, 2020
Ribociclib Drug-Drug Interactions: Clinical Evaluations and Physiologically-Based Pharmacokinetic Modeling to Guide Drug Labeling
Tanay S Samant, Felix Huth, Kenichi Umehara, et al.
Clinical Pharmacology and Therapeutics
|
November 15, 2017
Ribociclib Bioavailability Is Not Affected by Gastric pH Changes or Food Intake: In Silico and Clinical Evaluations
Tanay S Samant, Shyeilla Dhuria, Yasong Lu, et al.
Clinical Pharmacokinetics
|
March 18, 2026
Pharmacokinetics of Asciminib 200 mg in the Presence of a Strong CYP3A4 Inducer, Phenytoin, in Healthy Participants
Matthias Hoch, Amanda J Taylor, Felix Huth, et al.
Molecular Pharmaceutics
|
June 7, 2023
Interlaboratory Variability in the Madin-Darby Canine Kidney Cell Proteome
Matthew D Harwood, Katharina Zettl, Manuel Weinheimer, et al.
Archives of Toxicology
|
July 18, 2024
Identification of reversible OATP1B1 and time-dependent CYP3A4 inhibition as the major risk factors for drug-induced cholestasis (DIC)
Vlasia Kastrinou-Lampou, Raquel Rodríguez-Pérez, Birk Poller, et al.
Clinical Pharmacokinetics
|
October 29, 2024
Clinical Pharmacology of Asciminib: A Review
Matthias Hoch, Felix Huth, Paul William Manley, et al.
Clinical Pharmacology and Therapeutics
|
September 26, 2023
Utilization of OATP1B Biomarker Coproporphyrin-I to Guide Drug-Drug Interaction Risk Assessment: Evaluation by the Pharmaceutical Industry
Ryota Kikuchi, Paresh P Chothe, Xiaoyan Chu, et al.
Drug Metabolism and Pharmacokinetics
|
January 6, 2026
Future directions in drug-drug interaction evaluations: Industry perspective on the ICH M12 guidance
Kenichi Umehara, Andrew Harrell, Chandra Prakash, et al.
Page
of 5