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Bioconjugate Chemistry|September 13, 2014
Mild method for succinimide hydrolysis on ADCs: impact on ADC potency, stability, exposure, and efficacyL Nathan Tumey, Manoj Charati, Tao He, et al.
Bioorganic & Medicinal Chemistry Letters|July 21, 2004
D-piece modifications of the hemiasterlin analog HTI-286 produce potent tubulin inhibitorsArie Zask, Gary Birnberg, Katherine Cheung, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society|January 3, 2023
Volumetric imaging of optically cleared and fluorescently labeled animal tissue (VIOLA) for quantifying the 3D biodistribution of nanoparticles at cellular resolution in tumor tissueNikolai Rakhilin, Bing Yang, Mary E Spilker, et al.
Bioorganic & Medicinal Chemistry Letters|September 30, 2004
Synthesis and activity of novel analogs of hemiasterlin as inhibitors of tubulin polymerization: modification of the A segmentAyako Yamashita, Emily B Norton, Joshua A Kaplan, et al.
Bioconjugate Chemistry|May 22, 2016
Determination of Antibody-Drug Conjugate Released Payload Species Using Directed in Vitro Assays and Mass Spectrometric InterrogationAndrew J Bessire, T Eric Ballard, Manoj Charati, et al.
The Journal of Biological Chemistry|October 7, 2021
Modulation of SF3B1 in the pre-mRNA spliceosome induces a RIG-I-dependent type I IFN responseAaron Y Chang, Yu Jerry Zhou, Sharanya Iyengar, et al.
Plos One|May 31, 2017
Multivalent peptidic linker enables identification of preferred sites of conjugation for a potent thialanstatin antibody drug conjugateSujiet Puthenveetil, Haiyin He, Frank Loganzo, et al.
Molecular Cancer Therapeutics|October 22, 2017
Caveolae-Mediated Endocytosis as a Novel Mechanism of Resistance to Trastuzumab Emtansine (T-DM1)Matthew Sung, Xingzhi Tan, Bingwen Lu, et al.
Biochemistry|May 4, 2005
Two photoaffinity analogues of the tripeptide, hemiasterlin, exclusively label alpha-tubulinMaria Nunes, Joshua Kaplan, Joseph Wooters, et al.
Molecular Cancer Therapeutics|October 16, 2004
Cells resistant to HTI-286 do not overexpress P-glycoprotein but have reduced drug accumulation and a point mutation in alpha-tubulinFrank Loganzo, Malathi Hari, Tami Annable, et al.
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