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The AAPS Journal|October 10, 2006
Protein aggregation and bioprocessingMary E M Cromwell, Eric Hilario, Fred JacobsonMabs|January 14, 2010
Charge-based analysis of antibodies with engineered cysteines: from multiple peaks to a single main peakXiaoying Nancy Chen, Mary Nguyen, Fred Jacobson, et al.Bioconjugate Chemistry|May 31, 2014
Statistical modeling of the drug load distribution on trastuzumab emtansine (Kadcyla), a lysine-linked antibody drug conjugateMichael T Kim, Yan Chen, Joseph Marhoul, et al.Bioconjugate Chemistry|July 27, 2016
Structural Characterization of Cross-Linked Species in Trastuzumab Emtansine (Kadcyla)Yan Chen, Michael T Kim, Laura Zheng, et al.Analytical Chemistry|October 18, 2019
Streamlined Characterization of an Antibody-Drug Conjugate by Two-Dimensional and Four-Dimensional Liquid Chromatography/Mass SpectrometryAlexandre Goyon, Michael Kim, Lu Dai, et al.Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|May 24, 2016
Investigation of low recovery in the free drug assay for antibody drug conjugates by size exclusion-reversed phase two dimensional-liquid chromatographyYi Li, Cinzia Stella, Laura Zheng, et al.Scientific Reports|August 13, 2017
Statistical characterization of therapeutic protein modificationsTsung-Heng Tsai, Zhiqi Hao, Qiuting Hong, et al.Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology|April 28, 2010
Phase I study of trastuzumab-DM1, an HER2 antibody-drug conjugate, given every 3 weeks to patients with HER2-positive metastatic breast cancerIan E Krop, Muralidhar Beeram, Shanu Modi, et al.Bioconjugate Chemistry|July 22, 2008
Anti-CD22-MCC-DM1 and MC-MMAF conjugates: impact of assay format on pharmacokinetic parameters determinationJean-Philippe Stephan, Pamela Chan, Chien Lee, et al.Journal of Pharmaceutical Sciences|September 23, 2023
CMC Regulatory Considerations for Antibody-Drug ConjugatesKaroline Bechtold-Peters, Andrea Ruggiero, Nienke Vriezen, et al.Pageof 1