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Molecular Cell|July 5, 2006
The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell deathDipanjan Chowdhury, Paul J Beresford, Pengcheng Zhu, et al.
Frontiers in Immunology|April 19, 2021
TREX1 as a Novel Immunotherapeutic TargetWayne O Hemphill, Sean R Simpson, Mingyong Liu, et al.
Autoimmunity|November 14, 2018
TREX1 D18N mice fail to process erythroblast DNA resulting in inflammation and dysfunctional erythropoiesisStephen L Rego, Scott Harvey, Sean R Simpson, et al.
European Journal of Immunology|February 3, 2022
Targeting Bcl6 in the TREX1 D18N murine model ameliorates autoimmunity by modulating T-follicular helper cells and germinal center B cellsRajkumar Venkatadri, Vikram Sabapathy, Murat Dogan, et al.
Journal of Immunology (Baltimore, Md. : 1950)|December 13, 2019
T Cells Produce IFN-α in the TREX1 D18N Model of Lupus-like AutoimmunitySean R Simpson, Stephen L Rego, Scott E Harvey, et al.
The Journal of Biological Chemistry|September 16, 2006
Structure of the Escherichia coli DNA polymerase III epsilon-HOT proofreading complexThomas W Kirby, Scott Harvey, Eugene F DeRose, et al.
Nano Letters|October 3, 2017
Solid-State Nanopore Analysis of Diverse DNA Base Modifications Using a Modular Enzymatic Labeling ProcessFanny Wang, Osama K Zahid, Brandi E Swain, et al.
Journal of Molecular Medicine (Berlin, Germany)|April 19, 2007
A mutation in TREX1 that impairs susceptibility to granzyme A-mediated cell death underlies familial chilblain lupusMin Ae Lee-Kirsch, Dipanjan Chowdhury, Scott Harvey, et al.
Antioxidants & Redox Signaling|April 12, 2017
The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox SwitchChristopher H Mauney, LeAnn C Rogers, Reuben S Harris, et al.
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