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Bioorganic & Medicinal Chemistry Letters|June 20, 2013
Discovery of novel oxazolidinedione derivatives as potent and selective mineralocorticoid receptor antagonistsChristine Yang, Hong C Shen, Zhicai Wu, et al.Bioorganic & Medicinal Chemistry Letters|June 2, 2009
Discovery of spirocyclic secondary amine-derived tertiary ureas as highly potent, selective and bioavailable soluble epoxide hydrolase inhibitorsHong C Shen, Fa-Xiang Ding, Siyi Wang, et al.ACS Medicinal Chemistry Letters|January 20, 2018
Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein KinaseDanqing Feng, Tesfaye Biftu, F Anthony Romero, et al.Bioorganic & Medicinal Chemistry Letters|March 18, 2014
Mineralocorticoid receptor antagonists: identification of heterocyclic amide replacements in the oxazolidinedione seriesJason M Cox, Hong D Chu, Christine Yang, et al.Bioorganic & Medicinal Chemistry Letters|April 19, 2017
Discovery of indazole aldosterone synthase (CYP11B2) inhibitors as potential treatments for hypertensionScott B Hoyt, Jerry Taylor, Clare London, et al.ACS Medicinal Chemistry Letters|May 6, 2015
Discovery of benzimidazole oxazolidinediones as novel and selective nonsteroidal mineralocorticoid receptor antagonistsChristine Yang, Jaume Balsells, Hong D Chu, et al.Journal of Medicinal Chemistry|November 11, 2011
Benzimidazolones: a new class of selective peroxisome proliferator-activated receptor γ (PPARγ) modulatorsWeiguo Liu, Fiona Lau, Kun Liu, et al.Molecular Endocrinology (Baltimore, Md.)|January 30, 2003
Distinct properties and advantages of a novel peroxisome proliferator-activated protein [gamma] selective modulatorJoel P Berger, Ann E Petro, Karen L Macnaul, et al.Journal of Medicinal Chemistry|October 17, 2017
Hit-to-Lead Optimization and Discovery of 5-((5-([1,1'-Biphenyl]-4-yl)-6-chloro-1H-benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic Acid (MK-3903): A Novel Class of Benzimidazole-Based Activators of AMP-Activated Protein KinasePing Lan, F Anthony Romero, Dariusz Wodka, et al.Bioorganic & Medicinal Chemistry Letters|May 11, 2016
Discovery of novel non-steroidal reverse indole mineralocorticoid receptor antagonistsAnthony K Ogawa, Ellen Vande Bunte, Rudrajit Mal, et al.Pageof 4