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Biorxiv : the Preprint Server for Biology
|
February 7, 2023
Combined KRAS<sup>G12C</sup> and SOS1 inhibition enhances and extends the anti-tumor response in KRAS<sup>G12C</sup>-driven cancers by addressing intrinsic and acquired resistance
Venu Thatikonda, Hengyu Lu, Sabine Jurado, et al.
Journal of Medicinal Chemistry
|
March 15, 2021
One Atom Makes All the Difference: Getting a Foot in the Door between SOS1 and KRAS
Juergen Ramharter, Dirk Kessler, Peter Ettmayer, et al.
Cancer Discovery
|
August 21, 2020
BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition
Marco H Hofmann, Michael Gmachl, Juergen Ramharter, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
July 24, 2019
Drugging an undruggable pocket on KRAS
Dirk Kessler, Michael Gmachl, Andreas Mantoulidis, et al.
Nature Cancer
|
August 5, 2024
Co-targeting SOS1 enhances the antitumor effects of KRAS<sup>G12C</sup> inhibitors by addressing intrinsic and acquired resistance
Venu Thatikonda, Hengyu Lyu, Sabine Jurado, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
February 13, 2020
Reply to Tran et al.: Dimeric KRAS protein-protein interaction stabilizers
Dirk Kessler, Andreas Gollner, Michael Gmachl, et al.
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Showing results (91-100 of 96) with videos related to
Sort By:
Page
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You have reached the last page of results.
This site can display upto 96 results.
Biorxiv : the Preprint Server for Biology
|
February 7, 2023
Combined KRAS<sup>G12C</sup> and SOS1 inhibition enhances and extends the anti-tumor response in KRAS<sup>G12C</sup>-driven cancers by addressing intrinsic and acquired resistance
Venu Thatikonda, Hengyu Lu, Sabine Jurado, et al.
Journal of Medicinal Chemistry
|
March 15, 2021
One Atom Makes All the Difference: Getting a Foot in the Door between SOS1 and KRAS
Juergen Ramharter, Dirk Kessler, Peter Ettmayer, et al.
Cancer Discovery
|
August 21, 2020
BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition
Marco H Hofmann, Michael Gmachl, Juergen Ramharter, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
July 24, 2019
Drugging an undruggable pocket on KRAS
Dirk Kessler, Michael Gmachl, Andreas Mantoulidis, et al.
Nature Cancer
|
August 5, 2024
Co-targeting SOS1 enhances the antitumor effects of KRAS<sup>G12C</sup> inhibitors by addressing intrinsic and acquired resistance
Venu Thatikonda, Hengyu Lyu, Sabine Jurado, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
February 13, 2020
Reply to Tran et al.: Dimeric KRAS protein-protein interaction stabilizers
Dirk Kessler, Andreas Gollner, Michael Gmachl, et al.
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of 10