Search research articles
Contact Us
Filters
Showing results (1-10 of 34) with videos related to
Page
of 4
Sort By:
Current Topics in Medicinal Chemistry
|
November 29, 2013
A unique industrial-academic collaboration towards the next generation of schizophrenia therapeutics
Gregor J Macdonald, Craig W Lindsley
Bioorganic & Medicinal Chemistry
|
March 23, 2011
Molecular properties affecting fast dissociation from the D2 receptor
Gary Tresadern, Jose Manuel Bartolome, Gregor J Macdonald, et al.
Journal of the American Chemical Society
|
August 29, 2002
A new method for the preparation of silyl enol ethers from carbonyl compounds and (trimethylsilyl)diazomethane in a regiospecific and highly stereoselective manner
Varinder K Aggarwal, Chris G Sheldon, Gregor J Macdonald, et al.
Chemmedchem
|
March 7, 2017
1,3,5-Trisubstituted Pyrazoles as Potent Negative Allosteric Modulators of the mGlu<sub>2/3</sub> Receptors
Michiel Van Gool, Sergio A Alonso De Diego, Oscar Delgado, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 11, 2011
Rational design and synthesis of aminopiperazinones as β-secretase (BACE) inhibitors
Gary Tresadern, Francisca Delgado, Oscar Delgado, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 26, 2009
Scaffold hopping from pyridones to imidazo[1,2-a]pyridines. New positive allosteric modulators of metabotropic glutamate 2 receptor
Gary Tresadern, Jose María Cid, Gregor J Macdonald, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 6, 2003
The design of 8,8-dimethyl[1,6]naphthyridines as potential anticonvulsant agents
Nigel E Austin, Michael S Hadley, John D Harling, et al.
Journal of Medicinal Chemistry
|
April 25, 2014
Discovery of a potent, selective, and orally active phosphodiesterase 10A inhibitor for the potential treatment of schizophrenia
José Manuel Bartolomé-Nebreda, Francisca Delgado, María Luz Martín-Martín, et al.
ACS Medicinal Chemistry Letters
|
January 21, 2022
A Brain-Penetrant and Bioavailable Pyrazolopiperazine BACE1 Inhibitor Elicits Sustained Reduction of Amyloid β In Vivo
Aldo Peschiulli, Daniel Oehlrich, Michiel Van Gool, et al.
Journal of Medicinal Chemistry
|
October 27, 2020
[1,2,4]Triazolo[1,5-<i>a</i>]pyrimidine Phosphodiesterase 2A Inhibitors: Structure and Free-Energy Perturbation-Guided Exploration
Gary Tresadern, Ingrid Velter, Andrés A Trabanco, et al.
Page
of 4
Search research articles
Search
Showing results (1-10 of 34) with videos related to
Sort By:
Page
of 4
Current Topics in Medicinal Chemistry
|
November 29, 2013
A unique industrial-academic collaboration towards the next generation of schizophrenia therapeutics
Gregor J Macdonald, Craig W Lindsley
Bioorganic & Medicinal Chemistry
|
March 23, 2011
Molecular properties affecting fast dissociation from the D2 receptor
Gary Tresadern, Jose Manuel Bartolome, Gregor J Macdonald, et al.
Journal of the American Chemical Society
|
August 29, 2002
A new method for the preparation of silyl enol ethers from carbonyl compounds and (trimethylsilyl)diazomethane in a regiospecific and highly stereoselective manner
Varinder K Aggarwal, Chris G Sheldon, Gregor J Macdonald, et al.
Chemmedchem
|
March 7, 2017
1,3,5-Trisubstituted Pyrazoles as Potent Negative Allosteric Modulators of the mGlu<sub>2/3</sub> Receptors
Michiel Van Gool, Sergio A Alonso De Diego, Oscar Delgado, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 11, 2011
Rational design and synthesis of aminopiperazinones as β-secretase (BACE) inhibitors
Gary Tresadern, Francisca Delgado, Oscar Delgado, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 26, 2009
Scaffold hopping from pyridones to imidazo[1,2-a]pyridines. New positive allosteric modulators of metabotropic glutamate 2 receptor
Gary Tresadern, Jose María Cid, Gregor J Macdonald, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 6, 2003
The design of 8,8-dimethyl[1,6]naphthyridines as potential anticonvulsant agents
Nigel E Austin, Michael S Hadley, John D Harling, et al.
Journal of Medicinal Chemistry
|
April 25, 2014
Discovery of a potent, selective, and orally active phosphodiesterase 10A inhibitor for the potential treatment of schizophrenia
José Manuel Bartolomé-Nebreda, Francisca Delgado, María Luz Martín-Martín, et al.
ACS Medicinal Chemistry Letters
|
January 21, 2022
A Brain-Penetrant and Bioavailable Pyrazolopiperazine BACE1 Inhibitor Elicits Sustained Reduction of Amyloid β In Vivo
Aldo Peschiulli, Daniel Oehlrich, Michiel Van Gool, et al.
Journal of Medicinal Chemistry
|
October 27, 2020
[1,2,4]Triazolo[1,5-<i>a</i>]pyrimidine Phosphodiesterase 2A Inhibitors: Structure and Free-Energy Perturbation-Guided Exploration
Gary Tresadern, Ingrid Velter, Andrés A Trabanco, et al.
Page
of 4