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Bioorganic & Medicinal Chemistry Letters|September 25, 2002
Benzodiazepine inhibitors of the MMPs and TACEFrances C Nelson, Efren Delos Santos, Jeremy I Levin, et al.Journal of Medicinal Chemistry|May 30, 2003
Synthesis and structure-activity relationship of alpha-sulfonylhydroxamic acids as novel, orally active matrix metalloproteinase inhibitors for the treatment of osteoarthritisVenkatesan Aranapakam, George T Grosu, Jamie M Davis, et al.Biochemical Society Symposium|November 1, 2003
Substrate specificity and inducibility of TACE (tumour necrosis factor alpha-converting enzyme) revisited: the Ala-Val preference, and induced intrinsic activityRoy A Black, John R Doedens, Rajeev Mahimkar, et al.International Immunopharmacology|November 9, 2004
Characterization of (2R, 3S)-2-([[4-(2-butynyloxy)phenyl]sulfonyl]amino)-N,3-dihydroxybutanamide, a potent and selective inhibitor of TNF-alpha converting enzymeYuhua Zhang, Martin Hegen, Jun Xu, et al.Peptides|April 1, 2006
A novel approach to identifying beta-secretase inhibitors: bis-statine peptide mimetics discovered using structure and spot synthesisKristie Grove Bridges, Rajiv Chopra, Laura Lin, et al.Journal of Medicinal Chemistry|May 30, 2003
Synthesis and structure-activity relationship of N-substituted 4-arylsulfonylpiperidine-4-hydroxamic acids as novel, orally active matrix metalloproteinase inhibitors for the treatment of osteoarthritisVenkatesan Aranapakam, Jamie M Davis, George T Grosu, et al.Molecular Cancer Therapeutics|February 4, 2015
Tumor cells chronically treated with a trastuzumab-maytansinoid antibody-drug conjugate develop varied resistance mechanisms but respond to alternate treatmentsFrank Loganzo, Xingzhi Tan, Matthew Sung, et al.Bioorganic & Medicinal Chemistry Letters|December 11, 2007
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1' substrate binding pocketLee D Jennings, Derek C Cole, Joseph R Stock, et al.Bioorganic & Medicinal Chemistry Letters|December 29, 2007
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pocketsDerek C Cole, Joseph R Stock, Rajiv Chopra, et al.Proceedings of the National Academy of Sciences of the United States of America|November 18, 2025
EVOLVE platform, a trispecific T cell engager with integrated CD2 costimulation, for the treatment of solid and hematologic tumorsOksana A Sergeeva, Guixian Jin, Mohosin Sarkar, et al.Pageof 2