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ACS Chemical Biology|June 23, 2025
Design of an Orally Bioavailable Small Molecule That Modulates the Microtubule-Associated Protein Tau's Pre-mRNA SplicingPeiyuan Zhang, Amirhossein Taghavi, Masahito Abe, et al.ACS Chemical Biology|August 1, 2013
Cell-permeable stapled peptides based on HIV-1 integrase inhibitors derived from HIV-1 gene productsWataru Nomura, Haruo Aikawa, Nami Ohashi, et al.Proceedings of the National Academy of Sciences of the United States of America|January 23, 2020
Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancerMatthew G Costales, Haruo Aikawa, Yue Li, et al.Journal of the American Chemical Society|May 5, 2020
Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect SplicingJonathan L Chen, Peiyuan Zhang, Masahito Abe, et al.Proceedings of the National Academy of Sciences of the United States of America|November 21, 2022
A blood-brain penetrant RNA-targeted small molecule triggers elimination of r(G4C2)exp in c9ALS/FTD via the nuclear RNA exosomeJessica A Bush, Samantha M Meyer, Rita Fuerst, et al.Science Translational Medicine|October 27, 2021
Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo ALS modelsJessica A Bush, Haruo Aikawa, Rita Fuerst, et al.Pageof 3