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Protein Engineering, Design & Selection : PEDS|February 4, 2010
Antibody affinity maturation in vitro using unconjugated peptide antigenHiroto Iwai, Bengü Oztürk, Masaki Ihara, et al.
Methods in Molecular Biology (Clifton, N.J.)|March 16, 2017
Creation of Antigen-Dependent β-Lactamase Fusion Protein Tethered by Circularly Permuted Antibody Variable DomainsHiroto Iwai, Miki Kojima-Misaizu, Jinhua Dong, et al.
Bioconjugate Chemistry|March 1, 2016
Creation of a Ligand-Dependent Enzyme by Fusing Circularly Permuted Antibody Variable Region DomainsHiroto Iwai, Miki Kojima-Misaizu, Jinhua Dong, et al.
Chembiochem : a European Journal of Chemical Biology|November 13, 2024
Concise Affinity-Based Purification of Ligated mRNA for Structure-Activity Relationship Studies of Nucleosugar Modification PatternsHiroki Yamada, Hiroto Iwai, Fumitaka Hashiya, et al.
Bioconjugate Chemistry|March 31, 2011
Activation of circularly permutated β-lactamase tethered to antibody domains by specific small moleculesMiki Kojima, Hiroto Iwai, Jinhua Dong, et al.
ACS Chemical Biology|January 12, 2022
Enhancement of Gene Knockdown on CD22-Expressing Cells by Chemically Modified Glycan Ligand-siRNA ConjugatesToshimasa Harumoto, Hiroto Iwai, Mari Tanigawa, et al.
RSC Chemical Biology|August 29, 2025
Characterization of nuclease stability and poly(A)-binding protein binding activity of chemically modified poly(A) tail for in vivo applicationsAtsushi Hashimoto, Yuma Kunitomo, Ittoku Kikuchi, et al.
ACS Medicinal Chemistry Letters|May 18, 2019
Simplifying the Chemical Structure of Cationic Lipids for siRNA-Lipid NanoparticlesTakeshi Kuboyama, Kaori Yagi, Tomoyuki Naoi, et al.
Nucleic Acids Research|May 7, 2022
Targeted delivery to macrophages and dendritic cells by chemically modified mannose ligand-conjugated siRNAKeiji Uehara, Toshimasa Harumoto, Asana Makino, et al.
Nature Communications|November 19, 2025
Position-specific ORF nucleoside-ribose modifications enabled by complete chemical synthesis enhance mRNA stability and translationHiroto Iwai, Yasuaki Kimura, Masakazu Honma, et al.
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