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Biorxiv : the Preprint Server for Biology
|
July 16, 2025
Discovery of an Achiral Small Molecule TREM2 Agonist with Improved Pharmacokinetic Profile and Validated Target Engagement
Shaoren Yuan, Farida El Gaamouch, Sungwoo Cho, et al.
Biorxiv : the Preprint Server for Biology
|
September 5, 2025
As48, a First-in-Class Dual-Function TREM2 Modulator: Receptor Activation and Shedding Inhibition
Sungwoo Cho, Farida El Gaamouch, Saurabh Upadhyay, et al.
ACS Medicinal Chemistry Letters
|
August 20, 2025
Discovery of a Small Molecule TREM2 Agonist with Improved In Vitro Pharmacokinetic Profile and Validated Target Engagement
Shaoren Yuan, Farida El Gaamouch, Sungwoo Cho, et al.
Signal Transduction and Targeted Therapy
|
December 5, 2024
New insights into protein-protein interaction modulators in drug discovery and therapeutic advance
Hossam Nada, Yongseok Choi, Sungdo Kim, et al.
Journal of Medicinal Chemistry
|
August 20, 2025
Discovery and Optimization of LAG-3-Targeted Small Molecules via DNA-Encoded Chemical Library (DEL) Screening for Cancer Immunotherapy
Somaya A Abdel-Rahman, Laura Calvo-Barreiro, Nelson García Vázquez, et al.
Biorxiv : the Preprint Server for Biology
|
June 12, 2025
TREM2 Activation by First-in-Class Direct Small Molecule Agonists: DEL Screening, Optimization, Biophysical Validation, and Functional Characterization
Hossam Nada, Farida El Gaamouch, Sungwoo Cho, et al.
Biomedicines
|
September 28, 2021
Development of New Meridianin/Leucettine-Derived Hybrid Small Molecules as Nanomolar Multi-Kinase Inhibitors with Antitumor Activity
Mohamed H Elsherbeny, Ahmed Elkamhawy, Hossam Nada, et al.
Computer Methods and Programs in Biomedicine
|
July 11, 2024
From pixels to druggable leads: A CADD strategy for the design and synthesis of potent DDR1 inhibitors
Hossam Nada, Sungdo Kim, Cho Jaemin, et al.
Biorxiv : the Preprint Server for Biology
|
August 8, 2025
HTS-Oracle: A Retrainable AI Platform for High-Confidence Hit Identification Across Difficult-to-Drug Targets
Hossam Nada, Laura Calvo-Barreiro, Sungwoo Cho, et al.
Medicinal Research Reviews
|
February 2, 2024
Natural products as IL-6 inhibitors for inflammatory diseases: Synthetic and SAR perspective
Dipesh S Harmalkar, Aneesh Sivaraman, Hossam Nada, et al.
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Search research articles
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Showing results (51-60 of 80) with videos related to
Sort By:
Page
of 8
Biorxiv : the Preprint Server for Biology
|
July 16, 2025
Discovery of an Achiral Small Molecule TREM2 Agonist with Improved Pharmacokinetic Profile and Validated Target Engagement
Shaoren Yuan, Farida El Gaamouch, Sungwoo Cho, et al.
Biorxiv : the Preprint Server for Biology
|
September 5, 2025
As48, a First-in-Class Dual-Function TREM2 Modulator: Receptor Activation and Shedding Inhibition
Sungwoo Cho, Farida El Gaamouch, Saurabh Upadhyay, et al.
ACS Medicinal Chemistry Letters
|
August 20, 2025
Discovery of a Small Molecule TREM2 Agonist with Improved In Vitro Pharmacokinetic Profile and Validated Target Engagement
Shaoren Yuan, Farida El Gaamouch, Sungwoo Cho, et al.
Signal Transduction and Targeted Therapy
|
December 5, 2024
New insights into protein-protein interaction modulators in drug discovery and therapeutic advance
Hossam Nada, Yongseok Choi, Sungdo Kim, et al.
Journal of Medicinal Chemistry
|
August 20, 2025
Discovery and Optimization of LAG-3-Targeted Small Molecules via DNA-Encoded Chemical Library (DEL) Screening for Cancer Immunotherapy
Somaya A Abdel-Rahman, Laura Calvo-Barreiro, Nelson García Vázquez, et al.
Biorxiv : the Preprint Server for Biology
|
June 12, 2025
TREM2 Activation by First-in-Class Direct Small Molecule Agonists: DEL Screening, Optimization, Biophysical Validation, and Functional Characterization
Hossam Nada, Farida El Gaamouch, Sungwoo Cho, et al.
Biomedicines
|
September 28, 2021
Development of New Meridianin/Leucettine-Derived Hybrid Small Molecules as Nanomolar Multi-Kinase Inhibitors with Antitumor Activity
Mohamed H Elsherbeny, Ahmed Elkamhawy, Hossam Nada, et al.
Computer Methods and Programs in Biomedicine
|
July 11, 2024
From pixels to druggable leads: A CADD strategy for the design and synthesis of potent DDR1 inhibitors
Hossam Nada, Sungdo Kim, Cho Jaemin, et al.
Biorxiv : the Preprint Server for Biology
|
August 8, 2025
HTS-Oracle: A Retrainable AI Platform for High-Confidence Hit Identification Across Difficult-to-Drug Targets
Hossam Nada, Laura Calvo-Barreiro, Sungwoo Cho, et al.
Medicinal Research Reviews
|
February 2, 2024
Natural products as IL-6 inhibitors for inflammatory diseases: Synthetic and SAR perspective
Dipesh S Harmalkar, Aneesh Sivaraman, Hossam Nada, et al.
Page
of 8