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Trends in Pharmacological Sciences|March 2, 2022
Targeting solute carriers to modulate receptor-ligand interactionsHubert J Sijben, Giulio Superti-Furga, Adriaan P IJzerman, et al.
International Journal of Molecular Sciences|February 15, 2022
MPP+-Induced Changes in Cellular Impedance as a Measure for Organic Cation Transporter (SLC22A1-3) Activity and InhibitionTamara A M Mocking, Hubert J Sijben, Yimé W Vermeulen, et al.
Scientific Reports|January 15, 2021
A study of the dopamine transporter using the TRACT assay, a novel in vitro tool for solute carrier drug discoveryHubert J Sijben, Julie J E van den Berg, Jeremy D Broekhuis, et al.
Frontiers in Molecular Biosciences|December 11, 2023
Molecular insights into disease-associated glutamate transporter (EAAT1 / SLC1A3) variants using in silico and in vitro approachesMarina Gorostiola González, Hubert J Sijben, Laura Dall' Acqua, et al.
Scientific Reports|June 11, 2021
Label-free high-throughput screening assay for the identification of norepinephrine transporter (NET/SLC6A2) inhibitorsHubert J Sijben, Wieke M van Oostveen, Peter B R Hartog, et al.
Frontiers in Pharmacology|June 9, 2022
Impedance-Based Phenotypic Readout of Transporter Function: A Case for Glutamate TransportersHubert J Sijben, Laura Dall' Acqua, Rongfang Liu, et al.
ACS Chemical Neuroscience|March 13, 2024
Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake AssaysLieve van Veggel, Tamara A M Mocking, Hubert J Sijben, et al.
Frontiers in Pharmacology|August 27, 2021
An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of TransportersVojtech Dvorak, Tabea Wiedmer, Alvaro Ingles-Prieto, et al.
Frontiers in Pharmacology|July 25, 2024
Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamilyDaniela Digles, Alvaro Ingles-Prieto, Vojtech Dvorak, et al.
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