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Cell Systems|February 22, 2024
A top variant identification pipeline for protein engineeringHui Chen, Zhike Lu, Lijia MaScientific Reports|July 18, 2023
Optimized minimal genome-wide human sgRNA libraryYangfan Zhou, Lixia Wang, Zhike Lu, et al.Cell Discovery|May 16, 2023
Deep sampling of gRNA in the human genome and deep-learning-informed prediction of gRNA activitiesHeng Zhang, Jianfeng Yan, Zhike Lu, et al.Cell Reports Methods|June 26, 2025
TAS-seq enables subcellular single-stranded adenosine profiling by signal peptide-assisted adenosine deaminationLixia Wang, Yangfan Zhou, Zhenxing Yu, et al.Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|April 6, 2024
The Transpeptidase Sortase A Binds Nucleic Acids and Mediates Mammalian Cell LabelingYingzheng Liu, Zhike Lu, Panfeng Wu, et al.Molecular Therapy. Methods & Clinical Development|July 21, 2025
Directed evolution of novel AAV variants using the MCMS library for enhanced CNS tropism and reduced liver targeting in miceQingkai Song, Jiamei Wu, Qingfeng Zhang, et al.Cell Reports|February 15, 2024
Machine learning-based prediction models to guide the selection of Cas9 variants for efficient gene editingJianbo Li, Panfeng Wu, Zhoutao Cao, et al.Cell Reports|January 2, 2025
Improved split prime editors enable efficient in vivo genome editingRongwei Wei, Zhenxing Yu, Lihong Ding, et al.Genome Biology|June 10, 2020
Direct-seq: programmed gRNA scaffold for streamlined scRNA-seq in CRISPR screenQingkai Song, Ke Ni, Min Liu, et al.Nature Communications|December 12, 2022
PEAC-seq adopts Prime Editor to detect CRISPR off-target and DNA translocationZhenxing Yu, Zhike Lu, Jingjing Li, et al.Pageof 1,212