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Bioorganic & Medicinal Chemistry Letters|February 17, 2005
Isoindolinone-based inhibitors of the MDM2-p53 protein-protein interactionIan R Hardcastle, Shafiq U Ahmed, Helen Atkins, et al.Journal of Medicinal Chemistry|March 21, 2007
Pyranone, thiopyranone, and pyridone inhibitors of phosphatidylinositol 3-kinase related kinases. Structure-activity relationships for DNA-dependent protein kinase inhibition, and identification of the first potent and selective inhibitor of the ataxia telangiectasia mutated kinaseJonathan J Hollick, Laurent J M Rigoreau, Celine Cano-Soumillac, et al.Journal of Medicinal Chemistry|December 23, 2016
Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-ArylaminopurinesChristopher R Coxon, Elizabeth Anscombe, Suzannah J Harnor, et al.Journal of Medicinal Chemistry|February 15, 2011
Isoindolinone inhibitors of the murine double minute 2 (MDM2)-p53 protein-protein interaction: structure-activity studies leading to improved potencyIan R Hardcastle, Junfeng Liu, Eric Valeur, et al.European Journal of Medicinal Chemistry|June 19, 2019
Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4Stephanie M Myers, Duncan C Miller, Lauren Molyneux, et al.Journal of Medicinal Chemistry|July 2, 2021
An Alkynylpyrimidine-Based Covalent Inhibitor That Targets a Unique Cysteine in NF-κB-Inducing KinaseIslam Al-Khawaldeh, Mohammed J Al Yasiri, Gregory G Aldred, et al.Journal of Medicinal Chemistry|March 24, 2021
Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein InteractionGianni Chessari, Ian R Hardcastle, Jong Sook Ahn, et al.Pageof 6