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Bioorganic & Medicinal Chemistry Letters|October 26, 2013
The sulfamide moiety affords higher inhibitory activity and oral bioavailability to a series of coumarin dual selective RAF/MEK inhibitorsToshihiro Aoki, Ikumi Hyohdoh, Noriyuki Furuichi, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Optimizing the Physicochemical Properties of Raf/MEK Inhibitors by Nitrogen ScanningToshihiro Aoki, Ikumi Hyohdoh, Noriyuki Furuichi, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Fluorine Scanning by Nonselective Fluorination: Enhancing Raf/MEK Inhibition while Keeping Physicochemical PropertiesIkumi Hyohdoh, Noriyuki Furuichi, Toshihiro Aoki, et al.
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