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Molecular Therapy : the Journal of the American Society of Gene Therapy|December 28, 2020
Clinical Applications of Single-Stranded Oligonucleotides: Current Landscape of Approved and In-Development TherapeuticsJuergen Scharner, Isabel AznarezNature Biotechnology|December 15, 2015
Antisense oligonucleotide-directed inhibition of nonsense-mediated mRNA decayTomoki T Nomakuchi, Frank Rigo, Isabel Aznarez, et al.Journal of Medical Genetics|May 4, 2007
Exon skipping through the creation of a putative exonic splicing silencer as a consequence of the cystic fibrosis mutation R553XIsabel Aznarez, Julian Zielenski, Johanna M Rommens, et al.Human Molecular Genetics|August 13, 2003
Characterization of disease-associated mutations affecting an exonic splicing enhancer and two cryptic splice sites in exon 13 of the cystic fibrosis transmembrane conductance regulator geneIsabel Aznarez, Elayne M Chan, Julian Zielenski, et al.Cell Reports|May 17, 2018
Mechanism of Nonsense-Mediated mRNA Decay Stimulation by Splicing Factor SRSF1Isabel Aznarez, Tomoki T Nomakuchi, Jaclyn Tetenbaum-Novatt, et al.Genetics and Molecular Research : GMR|February 14, 2004
Cystic fibrosis in UruguayGerardo Luzardo, Isabel Aznarez, Beatriz Crispino, et al.Genome Research|May 6, 2008
A systematic analysis of intronic sequences downstream of 5' splice sites reveals a widespread role for U-rich motifs and TIA1/TIAL1 proteins in alternative splicing regulationIsabel Aznarez, Yoseph Barash, Ofer Shai, et al.Science Translational Medicine|August 28, 2020
Antisense oligonucleotides increase Scn1a expression and reduce seizures and SUDEP incidence in a mouse model of Dravet syndromeZhou Han, Chunling Chen, Anne Christiansen, et al.Nature Communications|July 11, 2020
Antisense oligonucleotide modulation of non-productive alternative splicing upregulates gene expressionKian Huat Lim, Zhou Han, Hyun Yong Jeon, et al.Nucleic Acid Therapeutics|September 12, 2024
Antisense Oligonucleotide STK-002 Increases OPA1 in Retina and Improves Mitochondrial Function in Autosomal Dominant Optic Atrophy CellsAditya Venkatesh, Taylor McKenty, Syed Ali, et al.Pageof 1