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Protein Science : a Publication of the Protein Society
|
December 24, 2003
Protein flexibility and intrinsic disorder
Predrag Radivojac, Zoran Obradovic, David K Smith, et al.
Journal of Medicinal Chemistry
|
June 19, 2015
Fragment-Based Discovery of a Small Molecule Inhibitor of Bruton's Tyrosine Kinase
Christopher R Smith, Douglas R Dougan, Mallareddy Komandla, et al.
The Journal of Biological Chemistry
|
November 26, 2002
Structural model of the regulatory domain of smooth muscle heavy meromyosin
Jan L Wahlstrom, M Allen Randall, J David Lawson, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 4, 2016
Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design-Part 2
Christopher McBride, Zacharia Cheruvallath, Mallareddy Komandla, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
A Back-to-Front Fragment-Based Drug Design Search Strategy Targeting the DFG-Out Pocket of Protein Tyrosine Kinases
Hidehisa Iwata, Hideyuki Oki, Kengo Okada, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 14, 2017
Structure-based optimization of 1H-imidazole-2-carboxamides as Axl kinase inhibitors utilizing a Mer mutant surrogate
Walter Keung, Amogh Boloor, Jason Brown, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 26, 2015
Fragment-based drug discovery of potent and selective MKK3/6 inhibitors
Mark Adams, Toshitake Kobayashi, J David Lawson, et al.
Bioinformatics (Oxford, England)
|
August 18, 2004
DisProt: a database of protein disorder
Slobodan Vucetic, Zoran Obradovic, Vladimir Vacic, et al.
Journal of Medicinal Chemistry
|
August 27, 2021
Discovery of the Bruton's Tyrosine Kinase Inhibitor Clinical Candidate TAK-020 (<i>S</i>)-5-(1-((1-Acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-2,4-dihydro-3<i>H</i>-1,2,4-triazol-3-one, by Fragment-Based Drug Design
Mark Sabat, Douglas R Dougan, Beverly Knight, et al.
Journal of Chemical Information and Modeling
|
October 17, 2024
Exploration of Cryptic Pockets Using Enhanced Sampling Along Normal Modes: A Case Study of KRAS <sup>G12D</sup>
Neha Vithani, She Zhang, Jeffrey P Thompson, et al.
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Search research articles
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Showing results (11-20 of 35) with videos related to
Sort By:
Page
of 4
Protein Science : a Publication of the Protein Society
|
December 24, 2003
Protein flexibility and intrinsic disorder
Predrag Radivojac, Zoran Obradovic, David K Smith, et al.
Journal of Medicinal Chemistry
|
June 19, 2015
Fragment-Based Discovery of a Small Molecule Inhibitor of Bruton's Tyrosine Kinase
Christopher R Smith, Douglas R Dougan, Mallareddy Komandla, et al.
The Journal of Biological Chemistry
|
November 26, 2002
Structural model of the regulatory domain of smooth muscle heavy meromyosin
Jan L Wahlstrom, M Allen Randall, J David Lawson, et al.
Bioorganic & Medicinal Chemistry Letters
|
May 4, 2016
Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design-Part 2
Christopher McBride, Zacharia Cheruvallath, Mallareddy Komandla, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
A Back-to-Front Fragment-Based Drug Design Search Strategy Targeting the DFG-Out Pocket of Protein Tyrosine Kinases
Hidehisa Iwata, Hideyuki Oki, Kengo Okada, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 14, 2017
Structure-based optimization of 1H-imidazole-2-carboxamides as Axl kinase inhibitors utilizing a Mer mutant surrogate
Walter Keung, Amogh Boloor, Jason Brown, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 26, 2015
Fragment-based drug discovery of potent and selective MKK3/6 inhibitors
Mark Adams, Toshitake Kobayashi, J David Lawson, et al.
Bioinformatics (Oxford, England)
|
August 18, 2004
DisProt: a database of protein disorder
Slobodan Vucetic, Zoran Obradovic, Vladimir Vacic, et al.
Journal of Medicinal Chemistry
|
August 27, 2021
Discovery of the Bruton's Tyrosine Kinase Inhibitor Clinical Candidate TAK-020 (<i>S</i>)-5-(1-((1-Acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-2,4-dihydro-3<i>H</i>-1,2,4-triazol-3-one, by Fragment-Based Drug Design
Mark Sabat, Douglas R Dougan, Beverly Knight, et al.
Journal of Chemical Information and Modeling
|
October 17, 2024
Exploration of Cryptic Pockets Using Enhanced Sampling Along Normal Modes: A Case Study of KRAS <sup>G12D</sup>
Neha Vithani, She Zhang, Jeffrey P Thompson, et al.
Page
of 4