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J Drysdale

Showing results (51-60 of 62) with videos related to

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Cancer Chemotherapy and Pharmacology|December 17, 2009
A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cellsAndrew J Massey, Douglas S Williamson, Helen Browne, et al.
Journal of Medicinal Chemistry|March 5, 2009
Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based designDouglas S Williamson, Jenifer Borgognoni, Alexandra Clay, et al.
Bioorganic & Medicinal Chemistry Letters|June 16, 2007
Discovery of a potent CDK2 inhibitor with a novel binding mode, using virtual screening and initial, structure-guided lead scopingChristine M Richardson, Claire L Nunns, Douglas S Williamson, et al.
Journal of Medicinal Chemistry|April 30, 2011
Adenosine-derived inhibitors of 78 kDa glucose regulated protein (Grp78) ATPase: insights into isoform selectivityAlba T Macias, Douglas S Williamson, Nicola Allen, et al.
Journal of Medicinal Chemistry|August 3, 2021
Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor InteractionDavid C McKinney, Brian J McMillan, Matthew J Ranaghan, et al.
Bioorganic & Medicinal Chemistry|September 29, 2012
Targeting conserved water molecules: design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimizationNicholas G M Davies, Helen Browne, Ben Davis, et al.
Bioorganic & Medicinal Chemistry Letters|March 31, 2000
Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysineR J Young, R M Beams, K Carter, et al.
Cancer Research|February 1, 2018
Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin CancerMathieu Unbekandt, Simone Belshaw, Justin Bower, et al.
Journal of Medicinal Chemistry|July 21, 2009
Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperonePaul A Brough, Xavier Barril, Jenifer Borgognoni, et al.
Cancer Research|April 17, 2008
NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasisSuzanne A Eccles, Andy Massey, Florence I Raynaud, et al.
Pageof 7

Showing results (51-60 of 62) with videos related to

Sort By:
Pageof 7
Cancer Chemotherapy and Pharmacology|December 17, 2009
A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cellsAndrew J Massey, Douglas S Williamson, Helen Browne, et al.
Journal of Medicinal Chemistry|March 5, 2009
Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based designDouglas S Williamson, Jenifer Borgognoni, Alexandra Clay, et al.
Bioorganic & Medicinal Chemistry Letters|June 16, 2007
Discovery of a potent CDK2 inhibitor with a novel binding mode, using virtual screening and initial, structure-guided lead scopingChristine M Richardson, Claire L Nunns, Douglas S Williamson, et al.
Journal of Medicinal Chemistry|April 30, 2011
Adenosine-derived inhibitors of 78 kDa glucose regulated protein (Grp78) ATPase: insights into isoform selectivityAlba T Macias, Douglas S Williamson, Nicola Allen, et al.
Journal of Medicinal Chemistry|August 3, 2021
Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor InteractionDavid C McKinney, Brian J McMillan, Matthew J Ranaghan, et al.
Bioorganic & Medicinal Chemistry|September 29, 2012
Targeting conserved water molecules: design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimizationNicholas G M Davies, Helen Browne, Ben Davis, et al.
Bioorganic & Medicinal Chemistry Letters|March 31, 2000
Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysineR J Young, R M Beams, K Carter, et al.
Cancer Research|February 1, 2018
Discovery of Potent and Selective MRCK Inhibitors with Therapeutic Effect on Skin CancerMathieu Unbekandt, Simone Belshaw, Justin Bower, et al.
Journal of Medicinal Chemistry|July 21, 2009
Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperonePaul A Brough, Xavier Barril, Jenifer Borgognoni, et al.
Cancer Research|April 17, 2008
NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasisSuzanne A Eccles, Andy Massey, Florence I Raynaud, et al.
Pageof 7