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Journal of Medicinal Chemistry|February 17, 1998
Discovery and development of the novel potent orally active thrombin inhibitor N-(9-hydroxy-9-fluorenecarboxy)prolyl trans-4-aminocyclohexylmethyl amide (L-372,460): coapplication of structure-based design and rapid multiple analogue synthesis on solid supportS F Brady, K J Stauffer, W C Lumma, et al.Journal of Medicinal Chemistry|September 9, 2000
Identification of MK-944a: a second clinical candidate from the hydroxylaminepentanamide isostere series of HIV protease inhibitorsB D Dorsey, C McDonough, S L McDaniel, et al.Journal of Medicinal Chemistry|August 14, 1998
Design and synthesis of a series of potent and orally bioavailable noncovalent thrombin inhibitors that utilize nonbasic groups in the P1 positionT J Tucker, S F Brady, W C Lumma, et al.Journal of Medicinal Chemistry|November 7, 1998
Efficacious, orally bioavailable thrombin inhibitors based on 3-aminopyridinone or 3-aminopyrazinone acetamide peptidomimetic templatesP E Sanderson, T A Lyle, K J Cutrona, et al.Journal of Medicinal Chemistry|June 23, 1999
Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinaseN J Liverton, J W Butcher, C F Claiborne, et al.Pageof 3