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Molecular Psychiatry|August 19, 2018
Arrestin recruitment to dopamine D2 receptor mediates locomotion but not incentive motivationPrashant Donthamsetti, Eduardo F Gallo, David C Buck, et al.Elife|January 28, 2020
Distinct inactive conformations of the dopamine D2 and D3 receptors correspond to different extents of inverse agonismJ Robert Lane, Ara M Abramyan, Pramisha Adhikari, et al.Communications Biology|March 24, 2022
OZITX, a pertussis toxin-like protein for occluding inhibitory G protein signalling including GαzAlastair C Keen, Maria Hauge Pedersen, Laura Lemel, et al.Journal of Medicinal Chemistry|February 11, 2017
Synthesis and Pharmacological Characterization of Novel trans-Cyclopropylmethyl-Linked Bivalent Ligands That Exhibit Selectivity and Allosteric Pharmacology at the Dopamine D3 Receptor (D3R)Vivek Kumar, Amy E Moritz, Thomas M Keck, et al.Brain, Behavior, and Immunity|June 21, 2016
β2-Adrenoceptors on tumor cells play a critical role in stress-enhanced metastasis in a mouse model of breast cancerAeson Chang, Caroline P Le, Adam K Walker, et al.The Journal of Biological Chemistry|January 24, 2019
The differential actions of clozapine and other antipsychotic drugs on the translocation of dopamine D2 receptors to the cell surfaceJoseph M Schrader, Craig M Irving, J Christopher Octeau, et al.Nature Chemical Biology|August 11, 2014
A new mechanism of allostery in a G protein-coupled receptor dimerJ Robert Lane, Prashant Donthamsetti, Jeremy Shonberg, et al.Journal of Medicinal Chemistry|January 20, 2023
Dopamine D3/D2 Receptor Ligands Based on Cariprazine for the Treatment of Psychostimulant Use Disorders That May Be Dual Diagnosed with Affective DisordersEmma S Gogarnoiu, Caleb D Vogt, Julie Sanchez, et al.ACS Chemical Biology|July 25, 2019
Molecular Determinants of the Intrinsic Efficacy of the Antipsychotic AripiprazoleCarmen Klein Herenbrink, Ravi Verma, Herman D Lim, et al.Nature Communications|February 25, 2016
The role of kinetic context in apparent biased agonism at GPCRsCarmen Klein Herenbrink, David A Sykes, Prashant Donthamsetti, et al.Pageof 33