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James B Murray

Showing results (1-10 of 32) with videos related to

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Methods in Enzymology|March 5, 2011
Experiences in fragment-based lead discoveryRoderick E Hubbard, James B Murray
Journal of Molecular Biology|September 2, 2003
A helical twist-induced conformational switch activates cleavage in the hammerhead ribozymeChristine M Dunham, James B Murray, William G Scott
Journal of Molecular Biology|January 10, 2002
A pH-dependent conformational change, rather than the chemical step, appears to be rate-limiting in the hammerhead ribozyme cleavage reactionJames B Murray, Christine M Dunham, William G Scott
Journal of the American Chemical Society|October 11, 2011
Shielded hydrogen bonds as structural determinants of binding kinetics: application in drug designPeter Schmidtke, F Javier Luque, James B Murray, et al.
Journal of Medicinal Chemistry|February 14, 2014
Off-rate screening (ORS) by surface plasmon resonance. An efficient method to kinetically sample hit to lead chemical space from unpurified reaction productsJames B Murray, Stephen D Roughley, Natalia Matassova, et al.
Biochimie|June 30, 2006
Crystal structure of the bacterial ribosomal decoding site complexed with amikacin containing the gamma-amino-alpha-hydroxybutyryl (haba) groupJiro Kondo, Boris François, Rupert J M Russell, et al.
Journal of the American Chemical Society|March 20, 2003
The complex of a designer antibiotic with a model aminoacyl site of the 30S ribosomal subunit revealed by X-ray crystallographyRupert J M Russell, James B Murray, Georg Lentzen, et al.
Chemistry & Biology|February 24, 2006
Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA siteJames B Murray, Samy O Meroueh, Rupert J M Russell, et al.
RNA (New York, N.Y.)|July 24, 2004
New tertiary constraints between the RNA components of active yeast spliceosomes: a photo-crosslinking studyDaniel E Ryan, Chang Hee Kim, James B Murray, et al.
Nucleic Acids Research|October 11, 2005
Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscodingBoris François, Rupert J M Russell, James B Murray, et al.
Pageof 4

Showing results (1-10 of 32) with videos related to

Sort By:
Pageof 4
Methods in Enzymology|March 5, 2011
Experiences in fragment-based lead discoveryRoderick E Hubbard, James B Murray
Journal of Molecular Biology|September 2, 2003
A helical twist-induced conformational switch activates cleavage in the hammerhead ribozymeChristine M Dunham, James B Murray, William G Scott
Journal of Molecular Biology|January 10, 2002
A pH-dependent conformational change, rather than the chemical step, appears to be rate-limiting in the hammerhead ribozyme cleavage reactionJames B Murray, Christine M Dunham, William G Scott
Journal of the American Chemical Society|October 11, 2011
Shielded hydrogen bonds as structural determinants of binding kinetics: application in drug designPeter Schmidtke, F Javier Luque, James B Murray, et al.
Journal of Medicinal Chemistry|February 14, 2014
Off-rate screening (ORS) by surface plasmon resonance. An efficient method to kinetically sample hit to lead chemical space from unpurified reaction productsJames B Murray, Stephen D Roughley, Natalia Matassova, et al.
Biochimie|June 30, 2006
Crystal structure of the bacterial ribosomal decoding site complexed with amikacin containing the gamma-amino-alpha-hydroxybutyryl (haba) groupJiro Kondo, Boris François, Rupert J M Russell, et al.
Journal of the American Chemical Society|March 20, 2003
The complex of a designer antibiotic with a model aminoacyl site of the 30S ribosomal subunit revealed by X-ray crystallographyRupert J M Russell, James B Murray, Georg Lentzen, et al.
Chemistry & Biology|February 24, 2006
Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA siteJames B Murray, Samy O Meroueh, Rupert J M Russell, et al.
RNA (New York, N.Y.)|July 24, 2004
New tertiary constraints between the RNA components of active yeast spliceosomes: a photo-crosslinking studyDaniel E Ryan, Chang Hee Kim, James B Murray, et al.
Nucleic Acids Research|October 11, 2005
Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscodingBoris François, Rupert J M Russell, James B Murray, et al.
Pageof 4