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SLAS Discovery : Advancing Life Sciences R & D|April 18, 2017
Determining the True Selectivity Profile of αv Integrin Ligands Using Radioligand Binding: Applying an Old Solution to a New ProblemJames E Rowedder, Steve B Ludbrook, Robert J SlackEuropean Journal of Medicinal Chemistry|September 1, 2020
Discovery of the first potent and selective αvβ5 integrin inhibitor based on an amide-containing coreRhys A Lippa, John Barrett, Sandeep Pal, et al.ACS Medicinal Chemistry Letters|February 21, 2015
Relative binding affinities of integrin antagonists by equilibrium dialysis and liquid chromatography-mass spectrometryWilliam J Tipping, Nkazimulo Tshuma, James Adams, et al.Chemistry (Weinheim an Der Bergstrasse, Germany)|March 5, 2020
Late-Stage Functionalization by Chan-Lam Amination: Rapid Access to Potent and Selective Integrin InhibitorsHenry Robinson, Steven A Oatley, James E Rowedder, et al.Journal of Medicinal Chemistry|January 28, 2017
Design and Elaboration of a Tractable Tricyclic Scaffold To Synthesize Druglike Inhibitors of Dipeptidyl Peptidase-4 (DPP-4), Antagonists of the C-C Chemokine Receptor Type 5 (CCR5), and Highly Potent and Selective Phosphoinositol-3 Kinase δ (PI3Kδ) InhibitorsCarolin Schwehm, Barrie Kellam, Aimie E Garces, et al.Chemmedchem|June 18, 2019
The Design of Potent, Selective and Drug-Like RGD αvβ1 Small-Molecule Inhibitors Derived from non-RGD α4β1 AntagonistsRichard J D Hatley, Tim N Barrett, Robert J Slack, et al.Bioorganic & Medicinal Chemistry Letters|November 22, 2016
The discovery of quinoline based single-ligand human H1 and H3 receptor antagonistsPanayiotis A Procopiou, Rachael A Ancliff, Paul M Gore, et al.ACS Medicinal Chemistry Letters|July 18, 2020
Design and Development of a Macrocyclic Series Targeting Phosphoinositide 3-Kinase δJonathan A Spencer, Ian R Baldwin, Nick Barton, et al.SLAS Discovery : Advancing Life Sciences R & D|November 22, 2022
A high-throughput MALDI-TOF MS biochemical screen for small molecule inhibitors of the antigen aminopeptidase ERAP1Leonie Müller, Amy K Burton, Chloe L Tayler, et al.ACS Medicinal Chemistry Letters|May 20, 2017
Design of Phthalazinone Amide Histamine H1 Receptor Antagonists for Use in RhinitisPanayiotis A Procopiou, Alison J Ford, Paul M Gore, et al.Pageof 2