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Journal of Medicinal Chemistry
|
September 7, 2018
Lowering Lipophilicity by Adding Carbon: One-Carbon Bridges of Morpholines and Piperazines
Sébastien L Degorce, Michael S Bodnarchuk, Iain A Cumming, et al.
Organic Letters
|
February 26, 2003
Highly selective entry to the azadirachtin skeleton via a Claisen rearrangement/radical cyclization sequence
Thomas Durand-Reville, Luca B Gobbi, Brian Lawrence Gray, et al.
European Journal of Pharmacology
|
June 24, 2015
Sustained wash-resistant receptor activation responses of GPR119 agonists
J Daniel Hothersall, Charlotte E Bussey, Alastair J Brown, et al.
Organic & Biomolecular Chemistry
|
July 18, 2008
Development of a practical Buchwald-Hartwig amine arylation protocol using a conveniently prepared (NHC)Pd(R-allyl)Cl catalyst
Mark J Cawley, F Geoffrey N Cloke, Richard J Fitzmaurice, et al.
Nature Reviews. Chemistry
|
December 13, 2025
Lessons learned in linking PROTACs from discovery to the clinic
Andy Pike, Esther C Y Lee, Iacovos N Michaelides, et al.
Journal of Medicinal Chemistry
|
January 3, 2020
Systematic Investigation of Lipophilicity Modulation by Aliphatic Fluorination Motifs
Benjamin Jeffries, Zhong Wang, Hannah R Felstead, et al.
Chemical Science
|
April 29, 2017
Enantioselective Narasaka-Heck cyclizations: synthesis of tetrasubstituted nitrogen-bearing stereocenters
Nicholas J Race, Adele Faulkner, Gabriele Fumagalli, et al.
Angewandte Chemie (International Ed. in English)
|
December 16, 2021
Relating Conformational Equilibria to Conformer-Specific Lipophilicities: New Opportunities in Drug Discovery
Bruno Linclau, Zhong Wang, Benjamin Jeffries, et al.
The Journal of Organic Chemistry
|
January 5, 2021
Skipped Fluorination Motifs: Synthesis of Building Blocks and Comparison of Lipophilicity Trends with Vicinal and Isolated Fluorination Motifs
Robert I Troup, Benjamin Jeffries, Raphael El-Bekri Saudain, et al.
ACS Chemical Biology
|
February 5, 2020
Structure-Guided Design and In-Cell Target Profiling of a Cell-Active Target Engagement Probe for PARP Inhibitors
Ryan T Howard, Paul Hemsley, Philip Petteruti, et al.
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of 7
Search research articles
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Showing results (11-20 of 64) with videos related to
Sort By:
Page
of 7
Journal of Medicinal Chemistry
|
September 7, 2018
Lowering Lipophilicity by Adding Carbon: One-Carbon Bridges of Morpholines and Piperazines
Sébastien L Degorce, Michael S Bodnarchuk, Iain A Cumming, et al.
Organic Letters
|
February 26, 2003
Highly selective entry to the azadirachtin skeleton via a Claisen rearrangement/radical cyclization sequence
Thomas Durand-Reville, Luca B Gobbi, Brian Lawrence Gray, et al.
European Journal of Pharmacology
|
June 24, 2015
Sustained wash-resistant receptor activation responses of GPR119 agonists
J Daniel Hothersall, Charlotte E Bussey, Alastair J Brown, et al.
Organic & Biomolecular Chemistry
|
July 18, 2008
Development of a practical Buchwald-Hartwig amine arylation protocol using a conveniently prepared (NHC)Pd(R-allyl)Cl catalyst
Mark J Cawley, F Geoffrey N Cloke, Richard J Fitzmaurice, et al.
Nature Reviews. Chemistry
|
December 13, 2025
Lessons learned in linking PROTACs from discovery to the clinic
Andy Pike, Esther C Y Lee, Iacovos N Michaelides, et al.
Journal of Medicinal Chemistry
|
January 3, 2020
Systematic Investigation of Lipophilicity Modulation by Aliphatic Fluorination Motifs
Benjamin Jeffries, Zhong Wang, Hannah R Felstead, et al.
Chemical Science
|
April 29, 2017
Enantioselective Narasaka-Heck cyclizations: synthesis of tetrasubstituted nitrogen-bearing stereocenters
Nicholas J Race, Adele Faulkner, Gabriele Fumagalli, et al.
Angewandte Chemie (International Ed. in English)
|
December 16, 2021
Relating Conformational Equilibria to Conformer-Specific Lipophilicities: New Opportunities in Drug Discovery
Bruno Linclau, Zhong Wang, Benjamin Jeffries, et al.
The Journal of Organic Chemistry
|
January 5, 2021
Skipped Fluorination Motifs: Synthesis of Building Blocks and Comparison of Lipophilicity Trends with Vicinal and Isolated Fluorination Motifs
Robert I Troup, Benjamin Jeffries, Raphael El-Bekri Saudain, et al.
ACS Chemical Biology
|
February 5, 2020
Structure-Guided Design and In-Cell Target Profiling of a Cell-Active Target Engagement Probe for PARP Inhibitors
Ryan T Howard, Paul Hemsley, Philip Petteruti, et al.
Page
of 7