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Cell|August 2, 2002
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machineryDo-Hyung Kim, D D Sarbassov, Siraj M Ali, et al.Current Biology : CB|July 23, 2004
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeletonD D Sarbassov, Siraj M Ali, Do-Hyung Kim, et al.Nature|August 20, 2025
Structural basis for the dynamic regulation of mTORC1 by amino acidsMax L Valenstein, Maximilian Wranik, Pranav V Lalgudi, et al.Nature Metabolism|July 29, 2020
Dihydroxyacetone phosphate signals glucose availability to mTORC1Jose M Orozco, Patrycja A Krawczyk, Sonia M Scaria, et al.Immunity|June 22, 2017
Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 KinaseJonatan Ersching, Alejo Efeyan, Luka Mesin, et al.Aging Cell|July 26, 2014
Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespanDudley W Lamming, Maria M Mihaylova, Pekka Katajisto, et al.Neurobiology of Disease|December 24, 2017
A mouse model of DEPDC5-related epilepsy: Neuronal loss of Depdc5 causes dysplastic and ectopic neurons, increased mTOR signaling, and seizure susceptibilityChristopher J Yuskaitis, Brandon M Jones, Rachel L Wolfson, et al.Cell Metabolism|May 7, 2020
A Nutrient-Sensing Transition at Birth Triggers Glucose-Responsive Insulin SecretionAharon Helman, Andrew L Cangelosi, Jeffrey C Davis, et al.Molecular Cell|April 30, 2003
GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTORDo-Hyung Kim, D D Sarbassov, Siraj M Ali, et al.ACS Chemical Biology|April 13, 2012
Selective ATP-competitive inhibitors of TOR suppress rapamycin-insensitive function of TORC2 in Saccharomyces cerevisiaeQingsong Liu, Tao Ren, Tara Fresques, et al.Pageof 25