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Clinical Pharmacokinetics|December 18, 2022
Impact of Sotorasib on the Pharmacokinetics and Pharmacodynamics of Metformin, a MATE1/2K Substrate, in Healthy SubjectsIrene Vuu, Jan Wahlstrom, Brett E HoukJournal of Clinical Pharmacology|June 19, 2024
Development and Evaluation of Ontogeny Functions of the Major UDP-Glucuronosyltransferase Enzymes to Underwrite Physiologically Based Pharmacokinetic Modeling in Pediatric PopulationsNashid Farhan, Upendra P Dahal, Jan WahlstromDrug Metabolism and Disposition: the Biological Fate of Chemicals|March 28, 2026
Enzyme-substrate-inactivator complex formation can impact time-dependent inhibition kineticsJaydeep Yadav, Jan Wahlstrom, Ken Korzekwa, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 20, 2021
Pharmacokinetics, Disposition, and Biotransformation of [14C]Omecamtiv Mecarbil in Healthy Male Subjects after a Single Intravenous or Oral DoseAshit Trivedi, Jan Wahlstrom, Mia Mackowski, et al.Archives of Biochemistry and Biophysics|July 16, 2003
A method for determining two substrates binding in the same active site of cytochrome P450BM3: an explanation of high energy omega product formationDan A Rock, Brandon N S Perkins, Jan Wahlstrom, et al.Sarcoidosis, Vasculitis, and Diffuse Lung Diseases : Official Journal of WASOG|May 24, 2008
Coeliac disease and risk of sarcoidosisJonas F Ludvigsson, Jan Wahlstrom, Johan Grunewald, et al.Journal of Pharmaceutical Sciences|December 5, 2016
Maximizing the Impact of Physiologically Based Oral Absorption Modeling and SimulationJohn I Chung, Ron C Kelly, Jan Wahlstrom, et al.Cancer Chemotherapy and Pharmacology|September 5, 2022
Absorption, metabolism and excretion of [14C]-sotorasib in healthy male subjects: characterization of metabolites and a minor albumin-sotorasib conjugateIrene Vuu, Upendra P Dahal, Zhe Wang, et al.FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|October 2, 2003
PDE4D plays a critical role in the control of airway smooth muscle contractionCéline Méhats, S-L Catherine Jin, Jan Wahlstrom, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 26, 2024
Xenografted Tumors Share Comparable Fraction Unbound and Can Be Surrogated by Mouse Lung TissueMin Wang, Sandip Kuldharan, Aravind Shenoy, et al.Pageof 3