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Jason Breed

Showing results (21-30 of 39) with videos related to

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Bioorganic & Medicinal Chemistry Letters|April 15, 2004
Imidazo[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitorsKate F Byth, Nicola Cooper, Janet D Culshaw, et al.
Bioorganic & Medicinal Chemistry Letters|December 13, 2005
SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitorsNicola M Heron, Malcolm Anderson, David P Blowers, et al.
Oncotarget|March 19, 2016
Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical useHarshnira Patani, Tom D Bunney, Nethaji Thiyagarajan, et al.
Journal of Medicinal Chemistry|February 17, 2016
Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell SurvivalJason G Kettle, Husam Alwan, Michal Bista, et al.
Structure (London, England : 1993)|January 17, 2004
Crystal structure of human thymidine phosphorylase in complex with a small molecule inhibitorRichard A Norman, Simon T Barry, Michael Bate, et al.
Bioorganic & Medicinal Chemistry Letters|August 3, 2010
Discovery of a novel class of triazolones as checkpoint kinase inhibitors--hit to lead explorationVibha Oza, Susan Ashwell, Patrick Brassil, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 20, 2016
Discovery of cofactor-specific, bactericidal Mycobacterium tuberculosis InhA inhibitors using DNA-encoded library technologyHolly H Soutter, Paolo Centrella, Matthew A Clark, et al.
Journal of Medicinal Chemistry|May 4, 2012
Discovery of checkpoint kinase inhibitor (S)-5-(3-fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide (AZD7762) by structure-based design and optimization of thiophenecarboxamide ureasVibha Oza, Susan Ashwell, Lynsie Almeida, et al.
ACS Medicinal Chemistry Letters|October 15, 2025
Focused Structure-Based Virtual Screening Identifies Novel Inhibitors of SOS1Silvia Bonomo, Floriane Gibault, Sharan K Bagal, et al.
Journal of Medicinal Chemistry|March 6, 2014
Cathepsin C inhibitors: property optimization and identification of a clinical candidateMark Furber, Anna-Karin Tiden, Philip Gardiner, et al.
Pageof 4

Showing results (21-30 of 39) with videos related to

Sort By:
Pageof 4
Bioorganic & Medicinal Chemistry Letters|April 15, 2004
Imidazo[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitorsKate F Byth, Nicola Cooper, Janet D Culshaw, et al.
Bioorganic & Medicinal Chemistry Letters|December 13, 2005
SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitorsNicola M Heron, Malcolm Anderson, David P Blowers, et al.
Oncotarget|March 19, 2016
Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical useHarshnira Patani, Tom D Bunney, Nethaji Thiyagarajan, et al.
Journal of Medicinal Chemistry|February 17, 2016
Potent and Selective Inhibitors of MTH1 Probe Its Role in Cancer Cell SurvivalJason G Kettle, Husam Alwan, Michal Bista, et al.
Structure (London, England : 1993)|January 17, 2004
Crystal structure of human thymidine phosphorylase in complex with a small molecule inhibitorRichard A Norman, Simon T Barry, Michael Bate, et al.
Bioorganic & Medicinal Chemistry Letters|August 3, 2010
Discovery of a novel class of triazolones as checkpoint kinase inhibitors--hit to lead explorationVibha Oza, Susan Ashwell, Patrick Brassil, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 20, 2016
Discovery of cofactor-specific, bactericidal Mycobacterium tuberculosis InhA inhibitors using DNA-encoded library technologyHolly H Soutter, Paolo Centrella, Matthew A Clark, et al.
Journal of Medicinal Chemistry|May 4, 2012
Discovery of checkpoint kinase inhibitor (S)-5-(3-fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide (AZD7762) by structure-based design and optimization of thiophenecarboxamide ureasVibha Oza, Susan Ashwell, Lynsie Almeida, et al.
ACS Medicinal Chemistry Letters|October 15, 2025
Focused Structure-Based Virtual Screening Identifies Novel Inhibitors of SOS1Silvia Bonomo, Floriane Gibault, Sharan K Bagal, et al.
Journal of Medicinal Chemistry|March 6, 2014
Cathepsin C inhibitors: property optimization and identification of a clinical candidateMark Furber, Anna-Karin Tiden, Philip Gardiner, et al.
Pageof 4