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Bioorganic & Medicinal Chemistry Letters
|
January 10, 2008
Novel 3-alkoxy-1H-pyrazolo[3,4-d]pyrimidines as EGFR and erbB2 receptor tyrosine kinase inhibitors
Richard Ducray, Peter Ballard, Bernard C Barlaam, et al.
ACS Medicinal Chemistry Letters
|
May 15, 2024
Vinylpyridine as a Tunable Covalent Warhead Targeting C797 in EGFR
Nils Pemberton, Nina Compagne, Argyrides Argyrou, et al.
Angewandte Chemie (International Ed. in English)
|
October 18, 2024
Site-Specific Quadruple-Functionalised Antibodies
Toby Journeaux, Michael B Geeson, Thomas V Murray, et al.
Toxicology Research
|
May 27, 2025
Use of new approach methodology for hepatic safety assessment of covalent inhibitor drug candidates
Sara Amberntsson, Alison J Foster, Bhavik Chouhan, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 29, 2011
Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series
Bernard Barlaam, Richard Ducray, Christine Lambert-van der Brempt, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 25, 2008
Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines
Catherine Bardelle, Darren Cross, Sara Davenport, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 2, 2005
5-Substituted 4-anilinoquinazolines as potent, selective and orally active inhibitors of erbB2 receptor tyrosine kinase
Peter Ballard, Robert H Bradbury, Laurent F A Hennequin, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 15, 2008
Inhibitors of the tyrosine kinase EphB4. Part 2: structure-based discovery and optimisation of 3,5-bis substituted anilinopyrimidines
Catherine Bardelle, Tanya Coleman, Darren Cross, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
March 30, 2020
The Pharmacokinetic-Pharmacodynamic (PKPD) Relationships of AZD3229, a Novel and Selective Inhibitor of KIT, in a Range of Mouse Xenograft Models of GIST
Venkatesh Pilla Reddy, Rana Anjum, Michael Grondine, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 30, 2006
Inhibitors of epidermal growth factor receptor tyrosine kinase: optimisation of potency and in vivo pharmacokinetics
Peter Ballard, Robert H Bradbury, Craig S Harris, et al.
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Search research articles
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Showing results (11-20 of 51) with videos related to
Sort By:
Page
of 6
Bioorganic & Medicinal Chemistry Letters
|
January 10, 2008
Novel 3-alkoxy-1H-pyrazolo[3,4-d]pyrimidines as EGFR and erbB2 receptor tyrosine kinase inhibitors
Richard Ducray, Peter Ballard, Bernard C Barlaam, et al.
ACS Medicinal Chemistry Letters
|
May 15, 2024
Vinylpyridine as a Tunable Covalent Warhead Targeting C797 in EGFR
Nils Pemberton, Nina Compagne, Argyrides Argyrou, et al.
Angewandte Chemie (International Ed. in English)
|
October 18, 2024
Site-Specific Quadruple-Functionalised Antibodies
Toby Journeaux, Michael B Geeson, Thomas V Murray, et al.
Toxicology Research
|
May 27, 2025
Use of new approach methodology for hepatic safety assessment of covalent inhibitor drug candidates
Sara Amberntsson, Alison J Foster, Bhavik Chouhan, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 29, 2011
Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series
Bernard Barlaam, Richard Ducray, Christine Lambert-van der Brempt, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 25, 2008
Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines
Catherine Bardelle, Darren Cross, Sara Davenport, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 2, 2005
5-Substituted 4-anilinoquinazolines as potent, selective and orally active inhibitors of erbB2 receptor tyrosine kinase
Peter Ballard, Robert H Bradbury, Laurent F A Hennequin, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 15, 2008
Inhibitors of the tyrosine kinase EphB4. Part 2: structure-based discovery and optimisation of 3,5-bis substituted anilinopyrimidines
Catherine Bardelle, Tanya Coleman, Darren Cross, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
March 30, 2020
The Pharmacokinetic-Pharmacodynamic (PKPD) Relationships of AZD3229, a Novel and Selective Inhibitor of KIT, in a Range of Mouse Xenograft Models of GIST
Venkatesh Pilla Reddy, Rana Anjum, Michael Grondine, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 30, 2006
Inhibitors of epidermal growth factor receptor tyrosine kinase: optimisation of potency and in vivo pharmacokinetics
Peter Ballard, Robert H Bradbury, Craig S Harris, et al.
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