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Journal of Medicinal Chemistry
|
January 10, 2023
Discovery of MK-8189, a Highly Potent and Selective PDE10A Inhibitor for the Treatment of Schizophrenia
Mark E Layton, Jeffrey C Kern, Timothy J Hartingh, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
June 1, 2013
Quantitative electroencephalography within sleep/wake states differentiates GABAA modulators eszopiclone and zolpidem from dual orexin receptor antagonists in rats
Steven V Fox, Anthony L Gotter, Spencer J Tye, et al.
Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|
December 26, 2025
Biomarkers
Wang Yuchuan, Helen J Mitchell, Susi Lee, et al.
Pain
|
October 9, 2024
Analgesia and peripheral c-fiber modulation by selective Na v 1.8 inhibition in rhesus
Joshua D Vardigan, Parul S Pall, Dillon S McDevitt, et al.
Science Translational Medicine
|
April 5, 2013
Orexin receptor antagonists differ from standard sleep drugs by promoting sleep at doses that do not disrupt cognition
Jason M Uslaner, Spencer J Tye, Donnie M Eddins, et al.
ACS Medicinal Chemistry Letters
|
July 19, 2023
Discovery of [<sup>11</sup>C]MK-8056: A Selective PET Imaging Agent for the Study of mGluR<sub>2</sub> Negative Allosteric Modulators
James J Perkins, Paul McQuade, Christopher J Bungard, et al.
Neuropharmacology
|
January 8, 2013
Mechanism based neurotoxicity of mGlu5 positive allosteric modulators--development challenges for a promising novel antipsychotic target
Sophie Parmentier-Batteur, Peter H Hutson, Karsten Menzel, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
June 5, 2020
MK-8719, a Novel and Selective <i>O</i>-GlcNAcase Inhibitor That Reduces the Formation of Pathological Tau and Ameliorates Neurodegeneration in a Mouse Model of Tauopathy
Xiaohai Wang, Wenping Li, Jacob Marcus, et al.
Journal of Medicinal Chemistry
|
March 25, 2016
Identification and in Vivo Evaluation of Liver X Receptor β-Selective Agonists for the Potential Treatment of Alzheimer's Disease
Shawn J Stachel, Celina Zerbinatti, Michael T Rudd, et al.
ACS Medicinal Chemistry Letters
|
August 16, 2023
Discovery of MK-8768, a Potent and Selective mGluR2 Negative Allosteric Modulator
Michael T Rudd, Peter J Manley, Barbara Hanney, et al.
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Search research articles
Search
Showing results (61-70 of 71) with videos related to
Sort By:
Page
of 8
Journal of Medicinal Chemistry
|
January 10, 2023
Discovery of MK-8189, a Highly Potent and Selective PDE10A Inhibitor for the Treatment of Schizophrenia
Mark E Layton, Jeffrey C Kern, Timothy J Hartingh, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|
June 1, 2013
Quantitative electroencephalography within sleep/wake states differentiates GABAA modulators eszopiclone and zolpidem from dual orexin receptor antagonists in rats
Steven V Fox, Anthony L Gotter, Spencer J Tye, et al.
Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|
December 26, 2025
Biomarkers
Wang Yuchuan, Helen J Mitchell, Susi Lee, et al.
Pain
|
October 9, 2024
Analgesia and peripheral c-fiber modulation by selective Na v 1.8 inhibition in rhesus
Joshua D Vardigan, Parul S Pall, Dillon S McDevitt, et al.
Science Translational Medicine
|
April 5, 2013
Orexin receptor antagonists differ from standard sleep drugs by promoting sleep at doses that do not disrupt cognition
Jason M Uslaner, Spencer J Tye, Donnie M Eddins, et al.
ACS Medicinal Chemistry Letters
|
July 19, 2023
Discovery of [<sup>11</sup>C]MK-8056: A Selective PET Imaging Agent for the Study of mGluR<sub>2</sub> Negative Allosteric Modulators
James J Perkins, Paul McQuade, Christopher J Bungard, et al.
Neuropharmacology
|
January 8, 2013
Mechanism based neurotoxicity of mGlu5 positive allosteric modulators--development challenges for a promising novel antipsychotic target
Sophie Parmentier-Batteur, Peter H Hutson, Karsten Menzel, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
June 5, 2020
MK-8719, a Novel and Selective <i>O</i>-GlcNAcase Inhibitor That Reduces the Formation of Pathological Tau and Ameliorates Neurodegeneration in a Mouse Model of Tauopathy
Xiaohai Wang, Wenping Li, Jacob Marcus, et al.
Journal of Medicinal Chemistry
|
March 25, 2016
Identification and in Vivo Evaluation of Liver X Receptor β-Selective Agonists for the Potential Treatment of Alzheimer's Disease
Shawn J Stachel, Celina Zerbinatti, Michael T Rudd, et al.
ACS Medicinal Chemistry Letters
|
August 16, 2023
Discovery of MK-8768, a Potent and Selective mGluR2 Negative Allosteric Modulator
Michael T Rudd, Peter J Manley, Barbara Hanney, et al.
Page
of 8