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Jean-Christophe Andrez

Showing results (1-10 of 11) with videos related to

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Beilstein Journal of Organic Chemistry|September 25, 2009
Mitomycins syntheses: a recent updateJean-Christophe Andrez
Organic Letters|May 31, 2011
A stereoselective oxidative polycyclization process mediated by a hypervalent iodine reagentSamuel Desjardins, Jean-Christophe Andrez, Sylvain Canesi
Organic Letters|September 4, 2010
Rapid formation of hindered cores using an oxidative Prins processJean-Christophe Andrez, Marc-André Giroux, Jessica Lucien, et al.
Cell Reports|September 21, 2018
Selective Na<sub>V</sub>1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic PainGirish Bankar, Samuel J Goodchild, Sarah Howard, et al.
Journal of Medicinal Chemistry|September 19, 2019
Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective Na<sub>V</sub>1.6 Inhibitors with Efficacy in Mouse Models of EpilepsyThilo Focken, Kristen Burford, Michael E Grimwood, et al.
Science (New York, N.Y.)|December 19, 2015
Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonistShivani Ahuja, Susmith Mukund, Lunbin Deng, et al.
Bioorganic & Medicinal Chemistry Letters|November 23, 2024
Discovery of novel cyclopentane carboxylic acids as potent and selective inhibitors of Na<sub>V</sub>1.7Shaoyi Sun, Sultan Chowdhury, Ivan Hemeon, et al.
Journal of Medicinal Chemistry|December 1, 2018
Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (Na<sub>V</sub>) 1.7 with Potent Analgesic ActivityShaoyi Sun, Qi Jia, Alla Y Zenova, et al.
British Journal of Pharmacology|June 26, 2024
The contribution of Na<sub>V</sub>1.6 to the efficacy of voltage-gated sodium channel inhibitors in wild type and Na<sub>V</sub>1.6 gain-of-function (GOF) mouse seizure controlJames P Johnson, Thilo Focken, Parisa Karimi Tari, et al.
Elife|March 2, 2022
NBI-921352, a first-in-class, Na<sub>V</sub>1.6 selective, sodium channel inhibitor that prevents seizures in <i>Scn8a</i> gain-of-function mice, and wild-type mice and ratsJ P Johnson, Thilo Focken, Kuldip Khakh, et al.
Pageof 2

Showing results (1-10 of 11) with videos related to

Sort By:
Pageof 2
Beilstein Journal of Organic Chemistry|September 25, 2009
Mitomycins syntheses: a recent updateJean-Christophe Andrez
Organic Letters|May 31, 2011
A stereoselective oxidative polycyclization process mediated by a hypervalent iodine reagentSamuel Desjardins, Jean-Christophe Andrez, Sylvain Canesi
Organic Letters|September 4, 2010
Rapid formation of hindered cores using an oxidative Prins processJean-Christophe Andrez, Marc-André Giroux, Jessica Lucien, et al.
Cell Reports|September 21, 2018
Selective Na<sub>V</sub>1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic PainGirish Bankar, Samuel J Goodchild, Sarah Howard, et al.
Journal of Medicinal Chemistry|September 19, 2019
Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective Na<sub>V</sub>1.6 Inhibitors with Efficacy in Mouse Models of EpilepsyThilo Focken, Kristen Burford, Michael E Grimwood, et al.
Science (New York, N.Y.)|December 19, 2015
Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonistShivani Ahuja, Susmith Mukund, Lunbin Deng, et al.
Bioorganic & Medicinal Chemistry Letters|November 23, 2024
Discovery of novel cyclopentane carboxylic acids as potent and selective inhibitors of Na<sub>V</sub>1.7Shaoyi Sun, Sultan Chowdhury, Ivan Hemeon, et al.
Journal of Medicinal Chemistry|December 1, 2018
Identification of Selective Acyl Sulfonamide-Cycloalkylether Inhibitors of the Voltage-Gated Sodium Channel (Na<sub>V</sub>) 1.7 with Potent Analgesic ActivityShaoyi Sun, Qi Jia, Alla Y Zenova, et al.
British Journal of Pharmacology|June 26, 2024
The contribution of Na<sub>V</sub>1.6 to the efficacy of voltage-gated sodium channel inhibitors in wild type and Na<sub>V</sub>1.6 gain-of-function (GOF) mouse seizure controlJames P Johnson, Thilo Focken, Parisa Karimi Tari, et al.
Elife|March 2, 2022
NBI-921352, a first-in-class, Na<sub>V</sub>1.6 selective, sodium channel inhibitor that prevents seizures in <i>Scn8a</i> gain-of-function mice, and wild-type mice and ratsJ P Johnson, Thilo Focken, Kuldip Khakh, et al.
Pageof 2