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Neuron|February 16, 2016
Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit FunctionDavid H Hackos, Patrick J Lupardus, Teddy Grand, et al.
Neuron|November 6, 2018
Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q AntibodiesBorislav Dejanovic, Melanie A Huntley, Ann De Mazière, et al.
Cell Reports|August 24, 2022
Disease-associated oligodendrocyte responses across neurodegenerative diseasesShristi Pandey, Kimberle Shen, Seung-Hye Lee, et al.
The Journal of Experimental Medicine|October 30, 2013
Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degenerationChristine D Pozniak, Arundhati Sengupta Ghosh, Alvin Gogineni, et al.
Nature Aging|April 28, 2023
Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse modelsBorislav Dejanovic, Tiffany Wu, Ming-Chi Tsai, et al.
Journal of Neuroinflammation|September 30, 2025
Modular inflammation network discovery from large-scale phenotypic screening in genetically heterogeneous mouse brainsMonica Xiong, Lisa A Miosge, Carolina Correa-Ospina, et al.
Cell Reports|August 22, 2019
Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and TauopathyTiffany Wu, Borislav Dejanovic, Vineela D Gandham, et al.
ACS Medicinal Chemistry Letters|January 21, 2017
GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved <i>in Vivo</i> ProfileElisia Villemure, Matthew Volgraf, Yu Jiang, et al.
Cell Reports|January 16, 2020
GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease ModelsJesse E Hanson, Keran Ma, Justin Elstrott, et al.
Journal of Medicinal Chemistry|February 28, 2016
Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based DesignMatthew Volgraf, Benjamin D Sellers, Yu Jiang, et al.
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