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Accounts of Chemical Research|March 18, 2021
Reimagining Druggability Using Chemoproteomic PlatformsJessica N Spradlin, Erika Zhang, Daniel K NomuraScientific Reports|September 24, 2020
Bardoxolone conjugation enables targeted protein degradation of BRD4Bingqi Tong, Mai Luo, Yi Xie, et al.Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry|March 14, 2022
De novo Design of SARS-CoV-2 Main Protease InhibitorsChristian Fischer, Nynke A Vepřek, Zisis Peitsinis, et al.Cell Chemical Biology|September 19, 2017
Covalent Ligand Discovery against Druggable Hotspots Targeted by Anti-cancer Natural ProductsElizabeth A Grossman, Carl C Ward, Jessica N Spradlin, et al.Cell Chemical Biology|January 29, 2021
Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product functionMai Luo, Jessica N Spradlin, Lydia Boike, et al.Journal of the American Chemical Society|January 7, 2022
Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation ApplicationsNathaniel J Henning, Andrew G Manford, Jessica N Spradlin, et al.Chemical Science|April 18, 2022
Photo-Brook rearrangement of acyl silanes as a strategy for photoaffinity probe designAnnika C S Page, Spencer O Scholz, Katherine N Keenan, et al.ACS Chemical Biology|June 23, 2020
A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABLBingqi Tong, Jessica N Spradlin, Luiz F T Novaes, et al.Nature Chemical Biology|June 19, 2019
Harnessing the anti-cancer natural product nimbolide for targeted protein degradationJessica N Spradlin, Xirui Hu, Carl C Ward, et al.Cancer Discovery|June 22, 2026
Selective Inhibition of KRASG13C Reveals an Increased Dependence on Wild-Type RAS Isoforms in Codon 13 RAS-Mutant CancersKyle J Seamon, Yongxian Zhuang, Yu Chi Yang, et al.Pageof 2