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Journal of Medicinal Chemistry|March 5, 2019
Discovery of Isaindigotone Derivatives as Novel Bloom's Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination RepairQi-Kun Yin, Chen-Xi Wang, Yu-Qing Wang, et al.European Journal of Medicinal Chemistry|December 2, 2022
Design, synthesis and evaluation of N3-substituted quinazolinone derivatives as potential Bloom's Syndrome protein (BLM) helicase inhibitor for sensitization treatment of colorectal cancerJia-Li Tu, Bi-Han Wu, Heng-Bo Wu, et al.Journal of Medicinal Chemistry|March 10, 2007
Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivativesTian-Miao Ou, Yu-Jing Lu, Chi Zhang, et al.Journal of Medicinal Chemistry|May 18, 2017
Discovery of Novel 11-Triazole Substituted Benzofuro[3,2-b]quinolone Derivatives as c-myc G-Quadruplex Specific Stabilizers via Click ChemistryDe-Ying Zeng, Guo-Tao Kuang, Shi-Ke Wang, et al.ACS Nano|September 15, 2022
Color-Switchable Nanosilicon Fluorescent ProbesHuai Chen, Jiang Xu, Yaping Wang, et al.Journal of Medicinal Chemistry|July 12, 2024
Development of Novel N-Acylhydrazone Derivatives with High Anti-obesity Activity and Improved Safety by Exploring the Pharmaceutical Properties of Aldehyde GroupZhi Jiang, Yu-Tao Hu, Shi-Yao Guo, et al.Diabetes, Obesity & Metabolism|November 12, 2024
L-aspartate ameliorates diet-induced obesity by increasing adipocyte energy expenditureShi-Yao Guo, Yu-Tao Hu, Yong Rao, et al.Acta Pharmaceutica Sinica. B|July 15, 2026
A novel NAMPT activator ameliorates obesity by repressing ACSL1-dependent lipid synthesisZhi Jiang, Yi-Xian Li, Dan-Dan Zhao, et al.Journal of Medicinal Chemistry|September 2, 2022
Discovery of a Novel G-Quadruplex and Histone Deacetylase (HDAC) Dual-Targeting Agent for the Treatment of Triple-Negative Breast CancerXin-Chen Jiang, Fang-Hai Tu, Li-Yuan Wei, et al.Journal of Medicinal Chemistry|September 30, 2008
5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferationYu-Jing Lu, Tian-Miao Ou, Jia-Heng Tan, et al.Pageof 14