Showing results (1-10 of 89) with videos related to

Sort By:
Pageof 9
Molecular and Cellular Endocrinology|December 9, 2008
Trafficking and quality control of the gonadotropin releasing hormone receptor in health and diseaseP Michael Conn, Jo Ann Janovick
Trends in Pharmacological Sciences|March 25, 2009
Drug development and the cellular quality control systemP Michael Conn, Jo Ann Janovick
Frontiers in Endocrinology|June 3, 2011
Pharmacoperone identification for therapeutic rescue of misfolded mutant proteinsP Michael Conn, Jo Ann Janovick
Methods in Enzymology|November 6, 2010
Use of pharmacoperones to reveal GPCR structural changes associated with constitutive activation and traffickingJo Ann Janovick, P Michael Conn
Proceedings of the National Academy of Sciences of the United States of America|February 18, 2010
Salt bridge integrates GPCR activation with protein traffickingJo Ann Janovick, P Michael Conn
Endocrine|January 8, 2004
Evolved regulation of gonadotropin-releasing hormone receptor cell surface expressionJo Ann Janovick, Alfredo Ulloa-Aguirre, P Michael Conn
Plos One|August 6, 2011
Therapeutic rescue of misfolded mutants: validation of primary high throughput screens for identification of pharmacoperone drugsJo Ann Janovick, Byung S Park, P Michael Conn
Methods in Enzymology|January 29, 2013
Therapeutic rescue of misfolded/mistrafficked mutants: automation-friendly high-throughput assays for identification of pharmacoperone drugs of GPCRsDavid C Smithson, Jo Ann Janovick, P Michael Conn
The Journal of Clinical Endocrinology and Metabolism|July 11, 2002
Rescue of hypogonadotropic hypogonadism-causing and manufactured GnRH receptor mutants by a specific protein-folding template: misrouted proteins as a novel disease etiology and therapeutic targetJo Ann Janovick, Guadalupe Maya-Nunez, P Michael Conn
The Journal of Clinical Endocrinology and Metabolism|October 5, 2002
Receptor-misrouting: an unexpectedly prevalent and rescuable etiology in gonadotropin-releasing hormone receptor-mediated hypogonadotropic hypogonadismAlfredo Leaños-Miranda, Jo Ann Janovick, P Michael Conn
Pageof 9