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Lab on a Chip|February 2, 2022
UV-DIB: label-free permeability determination using droplet interface bilayersRobert Strutt, Felix Sheffield, Nathan E Barlow, et al.Journal of Medicinal Chemistry|November 7, 2023
Integrated Direct-to-Biology Platform for the Nanoscale Synthesis and Biological Evaluation of PROTACsRebecca Stevens, Enrique Bendito-Moll, David J Battersby, et al.Journal of Medicinal Chemistry|March 13, 2024
Structure-Guided Design and Optimization of Covalent VHL-Targeted Sulfonyl Fluoride PROTACsRishi R Shah, Elena De Vita, Preethi S Sathyamurthi, et al.ACS Chemical Biology|February 27, 2019
PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent BindingChristopher P Tinworth, Hannah Lithgow, Lars Dittus, et al.Bioorganic & Medicinal Chemistry Letters|May 6, 2003
The design of 8,8-dimethyl[1,6]naphthyridines as potential anticonvulsant agentsNigel E Austin, Michael S Hadley, John D Harling, et al.Journal of Medicinal Chemistry|February 22, 2002
Identification of novel inhibitors of the transforming growth factor beta1 (TGF-beta1) type 1 receptor (ALK5)James F Callahan, Joelle L Burgess, James A Fornwald, et al.The Journal of Biological Chemistry|August 13, 2013
Discovery of novel irreversible inhibitors of interleukin (IL)-2-inducible tyrosine kinase (Itk) by targeting cysteine 442 in the ATP pocketJohn D Harling, Angela M Deakin, Sébastien Campos, et al.ACS Chemical Biology|July 23, 2020
Structural Insights into PROTAC-Mediated Degradation of Bcl-xLChun-Wa Chung, Han Dai, Esther Fernandez, et al.Chemical Communications (Cambridge, England)|September 6, 2022
Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs)Qisi Zhang, Cyrille S Kounde, Milon Mondal, et al.Bioorganic & Medicinal Chemistry Letters|June 14, 2005
(1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: a novel class of potent MSK-1-inhibitorsMark J Bamford, Michael J Alberti, Nicholas Bailey, et al.Pageof 3