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Biochemical Pharmacology|December 3, 2014
Chemical inhibitor targeting the replication protein A-DNA interaction increases the efficacy of Pt-based chemotherapy in lung and ovarian cancerAkaash K Mishra, Silvana S Dormi, Alaina M Turchi, et al.
DNA Repair|January 22, 2008
ATM mediates repression of DNA end-degradation in an ATP-dependent mannerElias A Rahal, Leigh A Henricksen, Yuling Li, et al.
Biorxiv : the Preprint Server for Biology|May 25, 2026
PARP1 catalytic domain mutations drive high-level resistance to saruparib while preserving DNA damage response vulnerabilitiesMatthew R Jordan, Jessica L Kersey, Joy E Garrett, et al.
Biochemistry|March 19, 2003
RPA phosphorylation in mitosis alters DNA binding and protein-protein interactionsGregory G Oakley, Steve M Patrick, Jiaqin Yao, et al.
Cancers|July 20, 2021
OB-Folds and Genome Maintenance: Targeting Protein-DNA Interactions for Cancer TherapySui Par, Sofia Vaides, Pamela S VanderVere-Carozza, et al.
Molecular and Cellular Biology|March 9, 2002
Partial reconstitution of human DNA mismatch repair in vitro: characterization of the role of human replication protein ACecilia Ramilo, Liya Gu, Shuangli Guo, et al.
The Journal of Biological Chemistry|March 31, 2009
Telomerase-associated protein 1, HSP90, and topoisomerase IIalpha associate directly with the BLM helicase in immortalized cells using ALT and modulate its helicase activity using telomeric DNA substratesSaumitri Bhattacharyya, Jeremy Keirsey, Beatriz Russell, et al.
Journal of Medicinal Chemistry|September 22, 2017
Design and Structure-Guided Development of Novel Inhibitors of the Xeroderma Pigmentosum Group A (XPA) Protein-DNA InteractionNavnath S Gavande, Pamela VanderVere-Carozza, Akaash K Mishra, et al.
Journal of Nucleic Acids|December 29, 2010
Targeting the OB-Folds of Replication Protein A with Small MoleculesVictor J Anciano Granadillo, Jennifer N Earley, Sarah C Shuck, et al.
ACS Medicinal Chemistry Letters|June 20, 2020
Structure-Guided Optimization of Replication Protein A (RPA)-DNA Interaction InhibitorsNavnath S Gavande, Pamela S VanderVere-Carozza, Katherine S Pawelczak, et al.
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