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Ebiomedicine|July 19, 2016
Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven CancersAnuradha Illendula, Jane Gilmour, Jolanta Grembecka, et al.Nature Chemical Biology|June 22, 2021
Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domainShirish Shukla, Weijiang Ying, Felicia Gray, et al.Nature Communications|May 15, 2021
Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activityDavid S Rogawski, Jing Deng, Hao Li, et al.Blood|March 18, 2026
Discovery and preclinical activity of the menin-KMT2A inhibitor ziftomenib in acute leukemia modelsHongzhi Miao, Tao Wu, Trupta Purohit, et al.Nature Medicine|March 31, 2015
Targeting the MLL complex in castration-resistant prostate cancerRohit Malik, Amjad P Khan, Irfan A Asangani, et al.The Journal of Clinical Investigation|December 20, 2019
Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemiaSzymon Klossowski, Hongzhi Miao, Katarzyna Kempinska, et al.The Lancet. Oncology|October 3, 2024
Ziftomenib in relapsed or refractory acute myeloid leukaemia (KOMET-001): a multicentre, open-label, multi-cohort, phase 1 trialEunice S Wang, Ghayas C Issa, Harry P Erba, et al.Pageof 8