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Journal of the American Chemical Society
|
September 3, 2020
Glycoside Hydrolases Restrict the Side Chain Conformation of Their Substrates To Gain Additional Transition State Stabilization
Jonathan C K Quirke, David Crich
ACS Catalysis
|
November 15, 2021
GH47 and Other Glycoside Hydrolases Catalyze Glycosidic Bond Cleavage with the Assistance of Substrate Super-arming at the Transition State
Jonathan C K Quirke, David Crich
ACS Catalysis
|
August 9, 2021
Side Chain Conformation Restriction in the Catalysis of Glycosidic Bond Formation by Leloir Glycosyltransferases, Glycoside Phosphorylases, and Transglycosidases
Jonathan C K Quirke, David Crich
JACS Au
|
November 28, 2025
Commonality of Mechanism in Glycoside Hydrolases, Nucleoside Hydrolases, and Phosphorylases: Importance of Side-Chain Conformation Preorganization
Po-Sen Tseng, Jonathan C K Quirke, W Jonathan Lin, et al.
Chemmedchem
|
April 6, 2022
Structure-Activity Relationships for 5'' Modifications of 4,5-Aminoglycoside Antibiotics
Jonathan C K Quirke, Girish C Sati, Amr Sonousi, et al.
Chemmedchem
|
October 2, 2020
An Advanced Apralog with Increased in vitro and in vivo Activity toward Gram-negative Pathogens and Reduced ex vivo Cochleotoxicity
Amr Sonousi, Jonathan C K Quirke, Prabuddha Waduge, et al.
Journal of the American Chemical Society
|
March 12, 2025
Identification of a Selective Anticancer Agent from a Collection of Complex-And-Diverse Compounds Synthesized from Stevioside
Rachel E Schaaf, Jonathan C K Quirke, Maryam Ghavami, et al.
Journal of the American Chemical Society
|
December 3, 2019
Apralogs: Apramycin 5-<i>O</i>-Glycosides and Ethers with Improved Antibacterial Activity and Ribosomal Selectivity and Reduced Susceptibility to the Aminoacyltranserferase (3)-IV Resistance Determinant
Jonathan C K Quirke, Parasuraman Rajasekaran, Vikram A Sarpe, et al.
Cancer Research Communications
|
December 5, 2023
Discovery of KRB-456, a KRAS G12D Switch-I/II Allosteric Pocket Binder That Inhibits the Growth of Pancreatic Cancer Patient-derived Tumors
Aslamuzzaman Kazi, Alok Ranjan, Vasantha Kumar M V, et al.
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of 1
Search research articles
Search
Showing results (1-10 of 9) with videos related to
Sort By:
Page
of 1
Journal of the American Chemical Society
|
September 3, 2020
Glycoside Hydrolases Restrict the Side Chain Conformation of Their Substrates To Gain Additional Transition State Stabilization
Jonathan C K Quirke, David Crich
ACS Catalysis
|
November 15, 2021
GH47 and Other Glycoside Hydrolases Catalyze Glycosidic Bond Cleavage with the Assistance of Substrate Super-arming at the Transition State
Jonathan C K Quirke, David Crich
ACS Catalysis
|
August 9, 2021
Side Chain Conformation Restriction in the Catalysis of Glycosidic Bond Formation by Leloir Glycosyltransferases, Glycoside Phosphorylases, and Transglycosidases
Jonathan C K Quirke, David Crich
JACS Au
|
November 28, 2025
Commonality of Mechanism in Glycoside Hydrolases, Nucleoside Hydrolases, and Phosphorylases: Importance of Side-Chain Conformation Preorganization
Po-Sen Tseng, Jonathan C K Quirke, W Jonathan Lin, et al.
Chemmedchem
|
April 6, 2022
Structure-Activity Relationships for 5'' Modifications of 4,5-Aminoglycoside Antibiotics
Jonathan C K Quirke, Girish C Sati, Amr Sonousi, et al.
Chemmedchem
|
October 2, 2020
An Advanced Apralog with Increased in vitro and in vivo Activity toward Gram-negative Pathogens and Reduced ex vivo Cochleotoxicity
Amr Sonousi, Jonathan C K Quirke, Prabuddha Waduge, et al.
Journal of the American Chemical Society
|
March 12, 2025
Identification of a Selective Anticancer Agent from a Collection of Complex-And-Diverse Compounds Synthesized from Stevioside
Rachel E Schaaf, Jonathan C K Quirke, Maryam Ghavami, et al.
Journal of the American Chemical Society
|
December 3, 2019
Apralogs: Apramycin 5-<i>O</i>-Glycosides and Ethers with Improved Antibacterial Activity and Ribosomal Selectivity and Reduced Susceptibility to the Aminoacyltranserferase (3)-IV Resistance Determinant
Jonathan C K Quirke, Parasuraman Rajasekaran, Vikram A Sarpe, et al.
Cancer Research Communications
|
December 5, 2023
Discovery of KRB-456, a KRAS G12D Switch-I/II Allosteric Pocket Binder That Inhibits the Growth of Pancreatic Cancer Patient-derived Tumors
Aslamuzzaman Kazi, Alok Ranjan, Vasantha Kumar M V, et al.
Page
of 1