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Jonathan L Chen

Showing results (21-30 of 31) with videos related to

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Bioorganic & Medicinal Chemistry Letters|July 13, 2024
NMR structures of small molecules bound to a model of a CUG RNA repeat expansionJonathan L Chen, Amirhossein Taghavi, Alexander J Frank, et al.
Journal of Medicinal Chemistry|June 8, 2021
A Druglike Small Molecule that Targets r(CCUG) Repeats in Myotonic Dystrophy Type 2 Facilitates Degradation by RNA Quality Control PathwaysSarah Wagner-Griffin, Masahito Abe, Raphael I Benhamou, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 31, 2019
Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse modelAlicia J Angelbello, Suzanne G Rzuczek, Kendra K Mckee, et al.
Biorxiv : the Preprint Server for Biology|September 4, 2024
NMR structures and magnetic force spectroscopy studies of small molecules binding to models of an RNA CAG repeat expansionAmirhossein Taghavi, Jonathan L Chen, Zhen Wang, et al.
ACS Chemical Biology|June 23, 2025
Design of an Orally Bioavailable Small Molecule That Modulates the Microtubule-Associated Protein Tau's Pre-mRNA SplicingPeiyuan Zhang, Amirhossein Taghavi, Masahito Abe, et al.
ACS Chemical Biology|November 16, 2020
Structural Features of Small Molecules Targeting the RNA Repeat Expansion That Causes Genetically Defined ALS/FTDAndrei Ursu, Kye Won Wang, Jessica A Bush, et al.
ACS Central Science|November 3, 2020
Targeting the SARS-CoV-2 RNA Genome with Small Molecule Binders and Ribonuclease Targeting Chimera (RIBOTAC) DegradersHafeez S Haniff, Yuquan Tong, Xiaohui Liu, et al.
Cell Chemical Biology|November 6, 2020
A Small Molecule that Binds an RNA Repeat Expansion Stimulates Its Decay via the Exosome ComplexAlicia J Angelbello, Raphael I Benhamou, Suzanne G Rzuczek, et al.
Cell Reports|November 27, 2024
Development of MAPT S305 mutation human iPSC lines exhibiting elevated 4R tau expression and functional alterations in neurons and astrocytesKathryn R Bowles, Chiara Pedicone, Derian A Pugh, et al.
Journal of the American Chemical Society|May 5, 2020
Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect SplicingJonathan L Chen, Peiyuan Zhang, Masahito Abe, et al.
Pageof 4

Showing results (21-30 of 31) with videos related to

Sort By:
Pageof 4
Bioorganic & Medicinal Chemistry Letters|July 13, 2024
NMR structures of small molecules bound to a model of a CUG RNA repeat expansionJonathan L Chen, Amirhossein Taghavi, Alexander J Frank, et al.
Journal of Medicinal Chemistry|June 8, 2021
A Druglike Small Molecule that Targets r(CCUG) Repeats in Myotonic Dystrophy Type 2 Facilitates Degradation by RNA Quality Control PathwaysSarah Wagner-Griffin, Masahito Abe, Raphael I Benhamou, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 31, 2019
Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse modelAlicia J Angelbello, Suzanne G Rzuczek, Kendra K Mckee, et al.
Biorxiv : the Preprint Server for Biology|September 4, 2024
NMR structures and magnetic force spectroscopy studies of small molecules binding to models of an RNA CAG repeat expansionAmirhossein Taghavi, Jonathan L Chen, Zhen Wang, et al.
ACS Chemical Biology|June 23, 2025
Design of an Orally Bioavailable Small Molecule That Modulates the Microtubule-Associated Protein Tau's Pre-mRNA SplicingPeiyuan Zhang, Amirhossein Taghavi, Masahito Abe, et al.
ACS Chemical Biology|November 16, 2020
Structural Features of Small Molecules Targeting the RNA Repeat Expansion That Causes Genetically Defined ALS/FTDAndrei Ursu, Kye Won Wang, Jessica A Bush, et al.
ACS Central Science|November 3, 2020
Targeting the SARS-CoV-2 RNA Genome with Small Molecule Binders and Ribonuclease Targeting Chimera (RIBOTAC) DegradersHafeez S Haniff, Yuquan Tong, Xiaohui Liu, et al.
Cell Chemical Biology|November 6, 2020
A Small Molecule that Binds an RNA Repeat Expansion Stimulates Its Decay via the Exosome ComplexAlicia J Angelbello, Raphael I Benhamou, Suzanne G Rzuczek, et al.
Cell Reports|November 27, 2024
Development of MAPT S305 mutation human iPSC lines exhibiting elevated 4R tau expression and functional alterations in neurons and astrocytesKathryn R Bowles, Chiara Pedicone, Derian A Pugh, et al.
Journal of the American Chemical Society|May 5, 2020
Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect SplicingJonathan L Chen, Peiyuan Zhang, Masahito Abe, et al.
Pageof 4