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Joseph P Vacca

Showing results (51-60 of 84) with videos related to

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Bioorganic & Medicinal Chemistry Letters|January 30, 2007
Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformationShaun R Stauffer, Matthew G Stanton, Alison R Gregro, et al.
Journal of Medicinal Chemistry|November 15, 2023
Discovery of KB-0742, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of CDK9 for MYC-Dependent CancersDavid B Freeman, Tamara D Hopkins, Peter J Mikochik, et al.
Journal of Medicinal Chemistry|December 14, 2004
Structure-based design of potent and selective cell-permeable inhibitors of human beta-secretase (BACE-1)Shawn J Stachel, Craig A Coburn, Thomas G Steele, et al.
Bioorganic & Medicinal Chemistry|July 28, 2006
Discovery of potent, selective 4-fluoroproline-based thrombin inhibitors with improved metabolic stabilityDonnette D Staas, Kelly L Savage, Vanessa L Sherman, et al.
Bioorganic & Medicinal Chemistry Letters|May 22, 2012
MK-8825: a potent and selective CGRP receptor antagonist with good oral activity in ratsIan M Bell, Craig A Stump, Steven N Gallicchio, et al.
Cancer Research|June 10, 2026
TNG917 is a Potent and Selective Inhibitor of Histone Lysine Methyltransferases EHMT1/2 that Enhances Anti-Tumor Immunity and Immunotherapy EfficacyAlvin Ziying Lu, Brian B Haines, Wenhai Zhang, et al.
Bioorganic & Medicinal Chemistry Letters|July 7, 2009
The identification of potent, orally bioavailable tricyclic CGRP receptor antagonistsIan M Bell, Rodney A Bednar, Halea A Corcoran, et al.
Bioorganic & Medicinal Chemistry Letters|June 5, 2012
Discovery of pyrazole carboxylic acids as potent inhibitors of rat long chain L-2-hydroxy acid oxidaseDinesh A Barawkar, Anish Bandyopadhyay, Anil Deshpande, et al.
Science (New York, N.Y.)|July 13, 2004
Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaquesDaria J Hazuda, Steven D Young, James P Guare, et al.
Journal of Medicinal Chemistry|November 30, 2004
Identification of a small molecule nonpeptide active site beta-secretase inhibitor that displays a nontraditional binding mode for aspartyl proteasesCraig A Coburn, Shawn J Stachel, Yue-Ming Li, et al.
Pageof 9

Showing results (51-60 of 84) with videos related to

Sort By:
Pageof 9
Bioorganic & Medicinal Chemistry Letters|January 30, 2007
Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformationShaun R Stauffer, Matthew G Stanton, Alison R Gregro, et al.
Journal of Medicinal Chemistry|November 15, 2023
Discovery of KB-0742, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of CDK9 for MYC-Dependent CancersDavid B Freeman, Tamara D Hopkins, Peter J Mikochik, et al.
Journal of Medicinal Chemistry|December 14, 2004
Structure-based design of potent and selective cell-permeable inhibitors of human beta-secretase (BACE-1)Shawn J Stachel, Craig A Coburn, Thomas G Steele, et al.
Bioorganic & Medicinal Chemistry|July 28, 2006
Discovery of potent, selective 4-fluoroproline-based thrombin inhibitors with improved metabolic stabilityDonnette D Staas, Kelly L Savage, Vanessa L Sherman, et al.
Bioorganic & Medicinal Chemistry Letters|May 22, 2012
MK-8825: a potent and selective CGRP receptor antagonist with good oral activity in ratsIan M Bell, Craig A Stump, Steven N Gallicchio, et al.
Cancer Research|June 10, 2026
TNG917 is a Potent and Selective Inhibitor of Histone Lysine Methyltransferases EHMT1/2 that Enhances Anti-Tumor Immunity and Immunotherapy EfficacyAlvin Ziying Lu, Brian B Haines, Wenhai Zhang, et al.
Bioorganic & Medicinal Chemistry Letters|July 7, 2009
The identification of potent, orally bioavailable tricyclic CGRP receptor antagonistsIan M Bell, Rodney A Bednar, Halea A Corcoran, et al.
Bioorganic & Medicinal Chemistry Letters|June 5, 2012
Discovery of pyrazole carboxylic acids as potent inhibitors of rat long chain L-2-hydroxy acid oxidaseDinesh A Barawkar, Anish Bandyopadhyay, Anil Deshpande, et al.
Science (New York, N.Y.)|July 13, 2004
Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaquesDaria J Hazuda, Steven D Young, James P Guare, et al.
Journal of Medicinal Chemistry|November 30, 2004
Identification of a small molecule nonpeptide active site beta-secretase inhibitor that displays a nontraditional binding mode for aspartyl proteasesCraig A Coburn, Shawn J Stachel, Yue-Ming Li, et al.
Pageof 9