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Journal of Medicinal Chemistry
|
September 24, 2009
p38alpha mitogen-activated protein kinase inhibitors: optimization of a series of biphenylamides to give a molecule suitable for clinical progression
Nicola M Aston, Paul Bamborough, Jacqueline B Buckton, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 11, 2008
Biphenyl amide p38 kinase inhibitors 3: Improvement of cellular and in vivo activity
Richard Angell, Nicola M Aston, Paul Bamborough, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 6, 2007
Biphenyl amide p38 kinase inhibitors 2: Optimisation and SAR
Richard M Angell, Tony D Angell, Paul Bamborough, et al.
Journal of Medicinal Chemistry
|
December 22, 2016
Discovery of a Potent, Cell Penetrant, and Selective p300/CBP-Associated Factor (PCAF)/General Control Nonderepressible 5 (GCN5) Bromodomain Chemical Probe
Philip G Humphreys, Paul Bamborough, Chun-Wa Chung, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 8, 2008
Biphenyl amide p38 kinase inhibitors 4: DFG-in and DFG-out binding modes
Richard M Angell, Tony D Angell, Paul Bamborough, et al.
Journal of Medicinal Chemistry
|
May 4, 2026
Targeting Activin Receptor-like Kinase 2 Using Heterobifunctional Protein Degraders
Daniel T Webb, Katherine L Jones, Natsuko Macabuag, et al.
Nature Communications
|
August 18, 2023
TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation
Jonathan D Worboys, Katherine N Vowell, Roseanna K Hare, et al.
Journal of Medicinal Chemistry
|
August 25, 2015
Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory Disease
Kenneth Down, Augustin Amour, Ian R Baldwin, et al.
Journal of Medicinal Chemistry
|
August 13, 2021
Discovery of a Novel Bromodomain and Extra Terminal Domain (BET) Protein Inhibitor, I-BET282E, Suitable for Clinical Progression
Katherine L Jones, Dominic M Beaumont, Sharon G Bernard, et al.
Journal of Medicinal Chemistry
|
November 15, 2022
Identification and Optimization of a Ligand-Efficient Benzoazepinone Bromodomain and Extra Terminal (BET) Family Acetyl-Lysine Mimetic into the Oral Candidate Quality Molecule I-BET432
Philip G Humphreys, Niall A Anderson, Paul Bamborough, et al.
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Search research articles
Search
Showing results (11-20 of 23) with videos related to
Sort By:
Page
of 3
Journal of Medicinal Chemistry
|
September 24, 2009
p38alpha mitogen-activated protein kinase inhibitors: optimization of a series of biphenylamides to give a molecule suitable for clinical progression
Nicola M Aston, Paul Bamborough, Jacqueline B Buckton, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 11, 2008
Biphenyl amide p38 kinase inhibitors 3: Improvement of cellular and in vivo activity
Richard Angell, Nicola M Aston, Paul Bamborough, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 6, 2007
Biphenyl amide p38 kinase inhibitors 2: Optimisation and SAR
Richard M Angell, Tony D Angell, Paul Bamborough, et al.
Journal of Medicinal Chemistry
|
December 22, 2016
Discovery of a Potent, Cell Penetrant, and Selective p300/CBP-Associated Factor (PCAF)/General Control Nonderepressible 5 (GCN5) Bromodomain Chemical Probe
Philip G Humphreys, Paul Bamborough, Chun-Wa Chung, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 8, 2008
Biphenyl amide p38 kinase inhibitors 4: DFG-in and DFG-out binding modes
Richard M Angell, Tony D Angell, Paul Bamborough, et al.
Journal of Medicinal Chemistry
|
May 4, 2026
Targeting Activin Receptor-like Kinase 2 Using Heterobifunctional Protein Degraders
Daniel T Webb, Katherine L Jones, Natsuko Macabuag, et al.
Nature Communications
|
August 18, 2023
TIGIT can inhibit T cell activation via ligation-induced nanoclusters, independent of CD226 co-stimulation
Jonathan D Worboys, Katherine N Vowell, Roseanna K Hare, et al.
Journal of Medicinal Chemistry
|
August 25, 2015
Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory Disease
Kenneth Down, Augustin Amour, Ian R Baldwin, et al.
Journal of Medicinal Chemistry
|
August 13, 2021
Discovery of a Novel Bromodomain and Extra Terminal Domain (BET) Protein Inhibitor, I-BET282E, Suitable for Clinical Progression
Katherine L Jones, Dominic M Beaumont, Sharon G Bernard, et al.
Journal of Medicinal Chemistry
|
November 15, 2022
Identification and Optimization of a Ligand-Efficient Benzoazepinone Bromodomain and Extra Terminal (BET) Family Acetyl-Lysine Mimetic into the Oral Candidate Quality Molecule I-BET432
Philip G Humphreys, Niall A Anderson, Paul Bamborough, et al.
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of 3