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The Journal of Experimental Medicine|September 1, 2004
Theophylline restores histone deacetylase activity and steroid responses in COPD macrophagesBorja G Cosio, Loukia Tsaprouni, Kazuhiro Ito, et al.
Biochemistry and Biophysics Reports|September 29, 2017
Repeated lipopolysaccharide exposure causes corticosteroid insensitive airway inflammation via activation of phosphoinositide-3-kinase δ pathwayKeitaro Ueda, Yuki Nishimoto, Genki Kimura, et al.
Journal of Clinical Medicine|August 23, 2020
Virus-Induced Asthma Exacerbations: SIRT1 Targeted ApproachYosuke Fukuda, Kaho Akimoto, Tetsuya Homma, et al.
Chest|February 4, 2009
Peroxynitrite elevation in exhaled breath condensate of COPD and its inhibition by fudosteineGrace O Osoata, Toyoyuki Hanazawa, Caterina Brindicci, et al.
Chest|December 17, 2011
Defect of adaptation to hypoxia in patients with COPD due to reduction of histone deacetylase 7Masako To, Satoshi Yamamura, Kenichi Akashi, et al.
Respiratory Research|March 26, 2016
Protein tyrosine phosphatase PTP-RR regulates corticosteroid sensitivityYoshiki Kobayashi, Kazuhiro Ito, Akira Kanda, et al.
Proceedings of the National Academy of Sciences of the United States of America|June 19, 2002
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expressionKazuhiro Ito, Sam Lim, Gaetano Caramori, et al.
American Journal of Respiratory and Critical Care Medicine|August 3, 2002
Expression and activity of histone deacetylases in human asthmatic airwaysKazuhiro Ito, Gaetano Caramori, Sam Lim, et al.
Plos Medicine|May 14, 2009
Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic diseaseKittipong Maneechotesuwan, Xin Yao, Kazuhiro Ito, et al.
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