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Pharmaceutical Research|March 30, 2021
Combination of cassette-dosing and microsampling for reduced animal usage for antibody pharmacokinetics in cynomolgus monkeys, wild-type mice, and human FcRn transgenic miceMiho Nagayasu, Kazuhisa Ozeki
Scientific Reports|October 2, 2020
Pharmacokinetic prediction of an antibody in mice based on an in vitro cell-based approach using target receptor-expressing cellsYuki Noguchi, Kazuhisa Ozeki, Hidetaka Akita
Pharmaceutical Research|June 2, 2023
Development of a New Method to Evaluate the Biodistribution of Antibodies Using Non-Radioactive Metal Labeling and Inductively Coupled Plasma Mass SpectrometryMiho Nagayasu, Yoko Takano, Kazuhisa Ozeki
Biological & Pharmaceutical Bulletin|September 3, 2019
Three-Compartment Model Analysis with Minimal Sampling Points in the Caco-2 Permeability AssayMiho Nagayasu, Kazuhisa Ozeki, Satomi Onoue
Biological & Pharmaceutical Bulletin|March 1, 2021
Evaluation of Methods to Assess CYP3A Induction Risk in Clinical Practice Using in Vitro Induction ParametersHaruka Tsutsui, Shino Kuramoto, Kazuhisa Ozeki
Biological & Pharmaceutical Bulletin|April 4, 2022
Cellular Binding and Internalization Assay for an Anti-FcγRIIB Antibody Using Human Liver Non-parenchymal CellsYuki Noguchi, Kazuhisa Ozeki, Hidetaka Akita
Scientific Reports|April 17, 2021
A cell based assay for evaluating binding and uptake of an antibody using hepatic nonparenchymal cellsYuki Noguchi, Kazuhisa Ozeki, Hiroaki Takesue, et al.
Mabs|July 7, 2017
Pharmacokinetics of an intracerebroventricularly administered antibody in ratsYuki Noguchi, Motohiro Kato, Kazuhisa Ozeki, et al.
Pharmaceutical Research|December 25, 2019
Simplified Method to Determine the Efflux Ratio on P-Glycoprotein Substrates Using Three-Compartment Model Analysis for Caco-2 Cell Assay DataMiho Nagayasu, Kazuhisa Ozeki, Yuuji Sakurai, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|October 17, 2023
Evaluation of the non-linearity of NA808 in liver not reflected in plasma using a rat pharmacokinetic study and PBPK modellingMizuki Yamane, Kazuhisa Ozeki, Ken Okano, et al.
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